Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMWB94K)

Drug Name

Evenamide Drug Info

Synonyms

1092977-61-1; 2-((3-Butoxyphenethyl)amino)-N,N-dimethylacetamide; UNII-ON5S6N53JS; ON5S6N53JS; MFCD28502433; 2-[(3-Butoxyphenethyl)amino]-N,N-dimethylacetamide; Evenamide [INN]; SCHEMBL3025285; CHEMBL3678076; 2-((2-(3-Butoxyphenyl)ethyl)amino)-N,N-dimethylacetamide; Acetamide, 2-((2-(3-butoxyphenyl)ethyl)amino)-N,N-dimethyl-; BDBM161090; NW-3509; SB18910; AS-48527; HY-17612; SY244487; CS-0014697; Q21098995; 2-[2-(3-butoxyphenyl)ethylamino]-N,N-dimethylacetamide; US9051240, 2-[2-(3-Butoxyphenyl)-ethylamino]-N,N-dimethylacetamide

Indication

Disease Entry	ICD 11	Status	REF
Schizophrenia	6A20	Phase 2	[1]

Cross-matching ID

PubChem CID: 25105689
CAS Number: CAS 1092977-61-1
TTD Drug ID: DMWB94K

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Voltage-gated sodium channel (Nav)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Lacosamide	DMVM6QR	Convulsion	8A68.Z	Approved	[3]
Eslicarbazepine	DMZREFQ	Seizure disorder	8A6Z	Approved	[3]
Tetrodotoxin	DMWMPRG	Bacterial infection	1A00-1C4Z	Approved	[3]
Cenobamate	DM8KLU9	Complex partial seizure	8A68.0	Approved	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Voltage-gated sodium channel (Nav)	TTIG65Q	NOUNIPROTAC	Blocker	[2]

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References

1	ClinicalTrials.gov (NCT04461119) Study to Determine the Safety, Tolerability, and Efficacy of Evenamide in Patients With Chronic Schizophrenia. U.S. National Institutes of Health.
2	Clinical pipeline report, company report or official report of Newron Pharmaceuticals.
3	Antibodies and venom peptides: new modalities for ion channels. Nat Rev Drug Discov. 2019 May;18(5):339-357.
4	Effects of cenobamate (YKP3089), a newly developed anti-epileptic drug, on voltage-gated sodium channels in rat hippocampal CA3 neurons. Eur J Pharmacol. 2019 Jul 15;855:175-182.