Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMWCBG8)

Drug Name
SR2211 Drug Info
Synonyms
1359164-11-6; sr-2211; SR 2211; CHEMBL2137199; 1,1,1,3,3,3-hexafluoro-2-[3-fluoro-4-[4-[[4-(pyridin-4-ylmethyl)piperazin-1-yl]methyl]phenyl]phenyl]propan-2-ol; 1,1,1,3,3,3-hexafluoro-2-[2-fluoro-4'-({4-[(pyridin-4-yl)methyl]piperazin-1-yl}methyl)[1,1'-biphenyl]-4-yl]propan-2-ol; 2-Fluoro-4'-[[4-(4-pyridinylmethyl)-1-piperazinyl]methyl]-; A,; A-bis(trifluoromethyl)-[1,1'-biphenyl]-4-methanol; 2-fluoro-4'-[[4-(4-pyridinylmethyl)-1-piperazinyl]methyl]-aa-bis(trifluoromethyl)-[1,1'-biphenyl]-4-methanol; MLS004256334; SCHEMBL13974431; C26H24F7N3O; GTPL10144; AOB1053; SYN5040; ML310; BDBM50005410; ZINC95571083; AKOS024458387; NCGC00379220-06; AS-16406; HY-16998; SMR003081219; B5743; CS-0013508; J3.525.407B; SR-03000002211; SR-03000002211-1; 1,1,1,3,3,3-hexafluoro-2-(2-fluoro-4'-((4-(pyridin-4-ylmethyl)piperazin-1-yl)methyl)-[1,1'-biphenyl]-4-yl)propan-2-ol; 2-Fluoro-4'-[[4-(4-pyridinylmethyl)-1-piperazinyl]methyl]-?,?-bis(trifluoromethyl)-[1,1'-biphenyl]-4-methanol; 2-Fluoro-4'-[[4-(4-pyridinylmethyl)-1-piperazinyl]methyl]-a,a-bis(trifluoromethyl)-[1,1'-biphenyl]-4-methanol; 2-Fluoro-4'-[[4-(4-pyridinylMethyl)-1-piperazinyl]Methyl]-alpha,alpha-bis(trifluoroMethyl)-[1,1'-biphenyl]-4-Methanol; L7P
Indication
Disease Entry ICD 11 Status REF
Autoimmune disease 4A40-4A45 Preclinical [1]
Cross-matching ID
PubChem CID
51035449
TTD Drug ID
DMWCBG8

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Nuclear receptor ROR-gamma (RORG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
GSK2981278 DM25YLM Plaque psoriasis EA90.0 Phase 2 [2]
LYC-55716 DMV8WU9 Non-small-cell lung cancer 2C25.Y Phase 2 [3]
VTP-43742 DMCA8G1 Psoriasis vulgaris EA90 Phase 2 [2]
ESR0114 DMUNM4D Plaque psoriasis EA90.0 Phase 1/2 [4]
AZD0284 DMHBEKM Plaque psoriasis EA90.0 Phase 1 [4]
ARN-6039 DM4D85V Multiple sclerosis 8A40 Phase 1 [5]
TAK-828 DMW43DL Crohn disease DD70 Phase 1 [2]
BBI-6000 DMTG9WM Psoriasis vulgaris EA90 Phase 1 [4]
JNJ-3534 DM49VWQ Psoriasis vulgaris EA90 Phase 1 [4]
JTE-451 DM01JU8 Plaque psoriasis EA90.0 Phase 1 [4]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Nuclear receptor ROR-gamma (RORG) TTGV6LY RORG_HUMAN Agonist [1]

References

1 Circadian rhythm as a therapeutic target. Nat Rev Drug Discov. 2021 Apr;20(4):287-307.
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
4 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
5 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)