Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMWDYLR)

Drug Name
4,6-dinitrobenzo[c][1,2,5]thiadiazole Drug Info
Synonyms
4,6-Dinitro-2,1,3-benzothiadiazole; 4,6-dinitrobenzo[c][1,2,5]thiadiazole; CHEMBL206140; 16408-06-3; NSC202427; AC1L76UW; AC1Q1Y7D; C6H2N4O4S; DTXSID90308123; MolPort-000-820-133; BYLOIWCTRDPRTP-UHFFFAOYSA-N; ZINC1736331; STK744333; BDBM50182130; 5,7-dinitro-2,1,3-benzothiadiazole; AKOS000544790; NSC-202427; MCULE-2301273439; 4,6-dinitrobenzo[c]1,2,5-thiadiazole; 4,6-Dinitro-benzo[1,2,5]thiadiazole; 2,1,3-Benzothiadiazole, 4,6-dinitro-; 4,6-Dinitro-2,1,3-benzothiadiazole #; NCI60_001699; ST032375; BAS 00731156
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
305451
CAS Number
CAS 16408-06-3
TTD Drug ID
DMWDYLR

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Patented Agent(s)
Download the Complete Related Drug List
Drug(s) Targeting Cytoplasmic thioredoxin reductase (TXNRD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fotemustine DMV62ED Solid tumour/cancer 2A00-2F9Z Approved [2]
Spermidine DMVJNFI Plaque psoriasis EA90.0 Phase 3 [2]
Golden phosphorous acetyletic compound 2 DMYJ15A N. A. N. A. Patented [3]
Terpyridineplatinum(II) complexe 3 DM54EFD N. A. N. A. Patented [3]
Terpyridineplatinum(II) complexe 4 DMOV86T N. A. N. A. Patented [3]
Golden phosphorous acetyletic compound 1 DMVAKUI N. A. N. A. Patented [3]
Acyl oxymethyl acrylamide ester derivative 1 DMXTUE1 N. A. N. A. Patented [3]
PMID27977313-Compound-18 DMIA3GH N. A. N. A. Patented [3]
Triazole gold complexe 1 DMCWES7 N. A. N. A. Patented [3]
4-aryl quinol derivative 2 DM7TW5Z N. A. N. A. Patented [3]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Cytoplasmic thioredoxin reductase (TXNRD1) TTR7UJ3 TRXR1_HUMAN Inhibitor [1]

References

1 Specific inhibitors of Plasmodium falciparum thioredoxin reductase as potential antimalarial agents. Bioorg Med Chem Lett. 2006 Apr 15;16(8):2283-92.
2 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
3 Thioredoxin reductase inhibitors: a patent review.Expert Opin Ther Pat. 2017 May;27(5):547-556.