Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMWFYJ4)

Drug Name

GB110 Drug Info

Synonyms

GB 110; GB-110

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Patented Agent(s)

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Drug(s) Targeting Proteinase activated receptor 2 (PAR2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Imidazopyridazine derivative 8	DMF7NXJ	Inflammation	1A00-CA43.1	Patented	[3]
Piperazine urea derivative 4	DM3K7IM	Inflammation	1A00-CA43.1	Patented	[3]
Piperidine derivative 2	DMHXMB4	Inflammation	1A00-CA43.1	Patented	[3]
Benzimidazole derivative 10	DML3PE4	N. A.	N. A.	Patented	[3]
Benzothiazine-carboxamide compound 2	DMMP2RT	Skin inflammation	EF20.Y	Patented	[3]
Peptide analog 71	DMSEKZG	N. A.	N. A.	Patented	[3]
Amidine compound 3	DMV0QJ4	Inflammation	1A00-CA43.1	Patented	[3]
Benzothiazine-carboxamide compound 4	DMSR918	Skin inflammation	EF20.Y	Patented	[3]
Quinazoline derivative 11	DMAH435	Chronic obstructive pulmonary disease	CA22	Patented	[3]
PMID26936077-Compound-13	DMXK6LV	Gastric ulcer	DA60	Patented	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Proteinase activated receptor 2 (PAR2)	TTQR74A	PAR2_HUMAN	Agonist	[2]

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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6657).
2	Novel agonists and antagonists for human protease activated receptor 2. J Med Chem. 2010 Oct 28;53(20):7428-40.
3	Protease activated receptor 2 (PAR2) modulators: a patent review (2010-2015).Expert Opin Ther Pat. 2016;26(4):471-83.