Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMWSR13)

Drug Name

2-Hydroxy-N-(3-phenyl-propyl)-benzamide Drug Info

Synonyms

2-hydroxy-N-(3-phenylpropyl)benzamide; CHEMBL290426; 153810-66-3; MLS000112389; 2-Hydroxy-N-(3-phenyl-propyl)-benzamide; AC1M4REE; Cambridge id 6816004; cid_2287872; MolPort-001-028-867; HMS2472G06; ZINC2989649; AC1Q7881; BDBM50282105; AKOS008913729; NE30179; MCULE-4556826159; JJ-3297; ST069062; SMR000108303; EN300-70444; AB00120250-01; (2-hydroxyphenyl)-N-(3-phenylpropyl)carboxamide; SR-01000522099; SR-01000522099-1

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 2287872
TTD Drug ID: DMWSR13

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Fungal Scytalone dehydratase (Fung SDH1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
(3-Phenyl-propyl)-quinazolin-4-yl-amine	DM1C90Y	Discovery agent	N.A.	Investigative	[1]
Isoquinolin-1-yl-(3-phenyl-propyl)-amine	DMDF26N	Discovery agent	N.A.	Investigative	[1]
Carpropamid	DMBKQ03	Discovery agent	N.A.	Investigative	[2]
5-Fluoro-2-hydroxy-N-isopropyl-benzamide	DMOI7ME	Discovery agent	N.A.	Investigative	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Fungal Scytalone dehydratase (Fung SDH1)	TT64EPS	SCYD_MAGO7	Inhibitor	[1]

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References

1	A diazine heterocycle replaces a six-membered hydrogen-bonded array in the active site of scytalone dehydratase, Bioorg. Med. Chem. Lett. 3(8):1605-1608 (1993).
2	Enzymatic characterization of scytalone dehydratase Val75Met variant found in melanin biosynthesis dehydratase inhibitor (MBI-D) resistant strains of the rice blast fungus. Biosci Biotechnol Biochem.2004 Mar;68(3):615-21.
3	Binding dynamics of two water molecules constrained within the scytalone dehydratase binding pocket. Bioorg Med Chem Lett. 2000 Jan 3;10(1):23-6.