General Information of Drug (ID: DMWTRUK)

Drug Name
PMID28766366-Compound-Scheme21Left Drug Info
Cross-matching ID
TTD Drug ID
DMWTRUK

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Patented Agent(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Harmine DMPA5WD Discovery agent N.A. Patented [1]
PMID28766366-Compound-Scheme21Right DMF3X40 N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme14BINDY DMBQ0RN N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme16DMAT DMQ5UEA N. A. N. A. Patented [1]
leucettine L41 DMBYND6 Discovery agent N.A. Investigative [2]
Drug Name Drug ID Indication ICD 11 Highest Status REF
PMID28766366-Compound-Scheme21Right DMF3X40 N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme14BINDY DMBQ0RN N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme2WO2012/098065bottom DMO4Q95 N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme7WO2012/098070upper DMGAQR5 N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme9EHT1610 DMMZGC8 N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme9EHT5372 DM0O18N N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme25-2 DM7OGWH N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme2WO2012/098065upper DMVJDRI N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme7WO2012/098070bottom DMQV6R0 N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme4Upper DMPH4JV N. A. N. A. Patented [1]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Harmine DMPA5WD Discovery agent N.A. Patented [1]
PMID28766366-Compound-Scheme21Right DMF3X40 N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme14BINDY DMBQ0RN N. A. N. A. Patented [1]
TG003 DMP4HR2 Discovery agent N.A. Patented [1]
PMID28766366-Compound-Scheme2WO2012/098065bottom DMO4Q95 N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme16DMAT DMQ5UEA N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme7WO2012/098070upper DMGAQR5 N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme9EHT1610 DMMZGC8 N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme9EHT5372 DM0O18N N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme25-2 DM7OGWH N. A. N. A. Patented [1]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Harmine DMPA5WD Discovery agent N.A. Patented [1]
PMID28766366-Compound-Scheme21Right DMF3X40 N. A. N. A. Patented [1]
PMID24900749C1a DMZPUSO Discovery agent N.A. Investigative [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Dual-specificity tyrosine-phosphorylation regulated kinase 1A (DYRK1A) TTSBVFO DYR1A_HUMAN Inhibitor [1]
Dual-specificity tyrosine-phosphorylation regulated kinase 1B (DYRK1B) TTYGQ8A DYR1B_HUMAN Inhibitor [1]
Dual-specificity tyrosine-phosphorylation regulated kinase 2 (DYRK2) TT84OS6 DYRK2_HUMAN Inhibitor [1]
Dual-specificity tyrosine-phosphorylation regulated kinase 3 (DYRK3) TTV4EX0 DYRK3_HUMAN Inhibitor [1]

References

1 Dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) inhibitors: a survey of recent patent literature.Expert Opin Ther Pat. 2017 Nov;27(11):1183-1199.
2 Leucettines, a class of potent inhibitors of cdc2-like kinases and dual specificity, tyrosine phosphorylation regulated kinases derived from the marine sponge leucettamine B: modulation of alternative pre-RNA splicing. J Med Chem. 2011 Jun 23;54(12):4172-86.
3 Structure and Property Based Design of Pyrazolo[1,5-a]pyrimidine Inhibitors of CK2 Kinase with Activity in Vivo. ACS Med Chem Lett. 2013 Jul 3;4(8):800-5.