Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMWUZP1)

Drug Name

PMID24157366C35 Drug Info

Synonyms

GTPL8554; BDBM50443348; US8669252, 12

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Patented Agent(s)

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Drug(s) Targeting Prolylcarboxypeptidase (PRCP)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cyclopentane carboxamide derivative 2	DMYP5FK	N. A.	N. A.	Patented	[2]
Piperidinyl pyrazole derivative 4	DMS8NFJ	N. A.	N. A.	Patented	[2]
Pyrrolidine carboxamide derivative 2	DMKDX6W	N. A.	N. A.	Patented	[2]
Piperidinyl pyrazole derivative 1	DMWAYXP	N. A.	N. A.	Patented	[2]
Benzodihydroisofuran derivative 1	DM249KU	N. A.	N. A.	Patented	[2]
Cyclohexane carboxamide derivative 2	DM1A0WU	N. A.	N. A.	Patented	[2]
Benzodihydroisofuran derivative 3	DMF6B1I	N. A.	N. A.	Patented	[2]
Benzodihydroisofuran derivative 4	DM5IH2O	N. A.	N. A.	Patented	[2]
Piperidinyl triazole derivative 4	DMOQJMU	N. A.	N. A.	Patented	[2]
Piperidinyl triazole derivative 5	DM4QVD0	N. A.	N. A.	Patented	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Prolylcarboxypeptidase (PRCP)	TTTJZ4M	PCP_HUMAN	Inhibitor	[1]

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References

1	Discovery and optimization of orally active cyclohexane-based prolylcarboxypeptidase (PrCP) inhibitors. Bioorg Med Chem Lett. 2013 Dec 1;23(23):6228-33.
2	Prolylcarboxypeptidase (PrCP) inhibitors and the therapeutic uses thereof: a patent review.Expert Opin Ther Pat. 2017 Oct;27(10):1077-1088.