General Information of Drug (ID: DMX2J57)

Drug Name
GT103 Drug Info
Indication
Disease Entry ICD 11 Status REF
Non-small-cell lung cancer 2C25.Y Phase 1 [1]
Cross-matching ID
TTD Drug ID
DMX2J57

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Drug(s) Targeting Complement factor H (CFH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Trumenba DMDHCK9 Meningitis 1D01 Approved [3]
TT-30 DMLDSX8 Autoimmune diabetes 5A10 Phase 1 [4]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Complement factor H (CFH) TTUW6OP CFAH_HUMAN Inhibitor [2]

References

1 ClinicalTrials.gov (NCT04314089) Phase Ib First in Human Dose Escalation of GT103 in Refractory, Advanced Stage Non-Small Cell Lung Cancer (TOP 1902). U.S. National Institutes of Health.
2 Clinical pipeline report, company report or official report of Grid Therapeutics.
3 2014 FDA drug approvals. Nat Rev Drug Discov. 2015 Feb;14(2):77-81.
4 The complement receptor 2/factor H fusion protein TT30 protects paroxysmal nocturnal hemoglobinuria erythrocytes from complement-mediated hemolysis and C3 fragment. Blood. 2012 Jun 28;119(26):6307-16.