Details of the Drug-Related molecule(s) Interaction Atlas

US9598431, 5 Drug Info

SCHEMBL18609480; BDBM302861; BDBM302862; US9598431, 5; US9598431, 4; (5'S)-5-Methyl-4',5'-dihydrospiro[piperidine-4,7'-thieno[2,3-c]pyran]; tert-Butyl (5'S)-5'-methyl-4',5'-dihydro-1H-spiro[piperidine-4,7'-thieno[2,3-c]pyran]-1-carboxylate

Cross-matching ID

PubChem CID

126669412

TTD Drug ID

DMXGF56

General Information of Drug (ID: DMXGF56)

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Patented Agent(s)

Investigative Drug(s)

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Drug(s) Targeting RAR-related orphan receptor-beta (RORB)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
US9598431, 2	DMILY1P	N. A.	N. A.	Patented	[1]
US9598431, 1	DMRVQ5Z	N. A.	N. A.	Patented	[1]
all-trans-4-oxo-retinoic acid	DMM2R1N	Discovery agent	N.A.	Investigative	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
RAR-related orphan receptor-beta (RORB)	TTGB2LZ	RORB_HUMAN	Inhibitor	[1]

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References

1	Compounds useful for inhibiting ROR-gamma-t. US9598431.
2	All-trans retinoic acid is a ligand for the orphan nuclear receptor ROR beta. Nat Struct Biol. 2003 Oct;10(10):820-5.