Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMXIRA0)

Drug Name
RLX030 Drug Info
Synonyms Serelaxin
Indication
Disease Entry ICD 11 Status REF
Acute heart failure BD10-BD13 Approval submitted [1]
Cross-matching ID
PubChem CID
71300755
CAS Number
CAS 99489-94-8
TTD Drug ID
DMXIRA0

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Relaxin receptor 1 (RXFP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
AZD5462 DM2QQZO Cardiovascular disease BA00-BE2Z Phase 1 [3]
ML290 DMPOX4Q Discovery agent N.A. Investigative [4]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Relaxin receptor 1 (RXFP1) TTMAHD1 RXFP1_HUMAN Modulator [2]

References

1 Clinical pipeline report, company report or official report of Novartis.
2 Design of the RELAXin in acute heart failure study. Am Heart J. 2012 Feb;163(2):149-55.e1.
3 Clinical pipeline report, company report or official report of AstraZeneca
4 Discovery, optimization, and biological activity of the first potent and selective small-molecule agonist series of human relaxin receptor 1 (RXFP1). Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010.