Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMXJWNS)

Drug Name

MM-093 Drug Info

Synonyms

ABI-001; Recombinant human alpha fetoprotein (autoimmune diseases), Merrimack; RhAFP (autoimmune diseases), Merrimack; Recombinant human alpha-fetoprotein (autoimmune disease), GTC Biotherapeutics

Indication

Disease Entry	ICD 11	Status	REF
Autoimmune diabetes	5A10	Phase 2	[1]

Cross-matching ID

TTD Drug ID: DMXJWNS

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Alpha-fetoprotein (AFP)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ET140202	DM87XVD	Hepatocellular carcinoma	2C12.02	Phase 1	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Alpha-fetoprotein (AFP)	TTCFEA1	FETA_HUMAN	Modulator	[2]

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References

1	ClinicalTrials.gov (NCT00458146) A Phase 2 Study to Evaluate the Efficacy and Safety of 60mg of MM-093 in Patients With Active Rheumatoid Arthritis. U.S. National Institutes of Health.
2	MM-093, a recombinant human alpha-fetoprotein for the potential treatment of rheumatoid arthritis and other autoimmune diseases. Curr Opin Mol Ther. 2007 Dec;9(6):603-10.
3	ClinicalTrials.gov (NCT03965546) Clinical Study of ET 140202 -T Cell Combined With TAE or Sorafenib in the Treatment of Advanced Liver Cancer. U.S.National Institutes of Health.