General Information of Drug (ID: DMXL7HO)

Drug Name
OLX10010 Drug Info
Synonyms OLX 101A
Indication
Disease Entry ICD 11 Status REF
Hypertrophic scars EE60 Phase 2 [1]
Cross-matching ID
TTD Drug ID
DMXL7HO

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
PF-06473871 DM9S3P7 Hypertrophic scars EE60 Phase 2 [3]
RXI-109 DMXG9ES Fibrosis GA14-GC01 Phase 2 [4]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
CCN2 messenger RNA (CCN2 mRNA) TTIL516 CCN2_HUMAN Inhibitor [2]

References

1 ClinicalTrials.gov (NCT04877756) Study to Evaluate Efficacy of OLX10010 in Reducing Recurrence of Hypertrophic Scarring After Scar Revision Surgery. U.S. National Institutes of Health.
2 Clinical pipeline report, company report or official report of Olix Pharmaceuticals.
3 A Placebo-controlled Study of PF-06473871 (Anti-Connective Tissue Growth Factor Antisense Oligonucleotide) in Reducing Hypertrophic Skin Scarring. Plast Reconstr Surg Glob Open. 2018 Sep 6;6(9):e1861.
4 The current state and future directions of RNAi-based therapeutics. Nat Rev Drug Discov. 2019 Jun;18(6):421-446.