Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMXLD07)

Drug Name
GSK4527223 Drug Info
Synonyms latozinemab; AL001
Indication
Disease Entry ICD 11 Status REF
Frontotemporal dementia 6D83 Phase 3 [1]
Amyotrophic lateral sclerosis 8B60.0 Phase 2 [1]
Cross-matching ID
TTD Drug ID
DMXLD07

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Sortilin (SORT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
AL001 DM7YBGH Frontotemporal dementia 6D83 Phase 3 [2]
GSK4527226 DMOVMGA Neurodegenerative disorder 8A20-8A23 Phase 1 [1]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Sortilin (SORT1) TTRX9AV SORT_HUMAN Not Available [1]

References

1 Clinical pipeline report, company report or official report of GlaxoSmithKline
2 Latozinemab, a novel progranulin-elevating therapy for frontotemporal dementia. J Transl Med. 2023 Jun 15;21(1):387.