Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMXOYK0)

Drug Name
arcaine Drug Info
Synonyms
arcaine; Tetramethylenediguanide; 1,4-Diguanidinobutane; N,N'''-1,4-Butanediylbisguanidine; Arcain; 544-05-8; 1-(4-guanidinobutyl)guanidine; CHEMBL102740; CHEBI:16652; 1,1'-(butane-1,4-diyl)diguanidine; Guanidine, N,N'''-1,4-butanediylbis-; A-8340; 1-(4-carbamimidamidobutyl)guanidine; 58585-47-0; 2,2'-butane-1,4-diyldiguanidine; Tocris-0389; Spectrum_001819; Prestwick2_000876; Spectrum5_001638; Prestwick1_000876; Prestwick0_000876; Spectrum3_001100; Spectrum2_000601; Prestwick3_000876; Spectrum4_001929; Lopac-A-0384
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
2227
ChEBI ID
CHEBI:16652
CAS Number
CAS 544-05-8
TTD Drug ID
DMXOYK0
VARIDT Drug ID
DR01015

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Acid-sensing ion channel 3 (ASIC3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
benzamil DM57SVW Discovery agent N.A. Investigative [3]
agmatine DMSBZ29 Discovery agent N.A. Investigative [2]
A-317567 DMGWO9J Discovery agent N.A. Investigative [2]
THA-902 DMKCY0X Fibromyalgia MG30.01 Investigative [2]
GMQ DMM0ZKQ Discovery agent N.A. Investigative [2]
APETX2 DM0JW2V Pain MG30-MG3Z Investigative [4]
⏷ Show the Full List of 6 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Acid-sensing ion channel 3 (ASIC3) TTLGDIS ASIC3_HUMAN Activator [2]

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4137).
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 686).
3 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 684).
4 Challenges in analgesic drug development. Clin Pharmacol Ther. 2009 Oct;86(4):447-50.