General Information of Drug (ID: DMXWG6Z)

Drug Name
A-798 Drug Info
Synonyms
A-429; A-655; A-665798; A-748; A-761; A-780748; MCHR-1 antagonists (obesity); Melanin concentrating hormone-1 receptor antagonists, Abbott; MCH-1 antagonists (obesity), Abbott; MCHR-1 antagonists (obesity), Abbott
Indication
Disease Entry ICD 11 Status REF
Obesity 5B81 Terminated [1]
Cross-matching ID
TTD Drug ID
DMXWG6Z

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Patented Agent(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
BMS-830216 DMCW71N Obesity 5B81 Phase 1 [3]
AZD1979 DMQ1OX4 Obesity 5B81 Phase 1 [4]
PMID25522065-Compound-27 DMXN4KB N. A. N. A. Patented [5]
PMID25522065-Compound-29 DMBNAK9 N. A. N. A. Patented [5]
PMID25522065-Compound-34 DMZDIRQ N. A. N. A. Patented [5]
PMID25522065-Compound-39 DM5YMQH N. A. N. A. Patented [5]
PMID25522065-Compound-40 DMCIQ01 N. A. N. A. Patented [5]
PMID25522065-Compound-11 DM410Z6 N. A. N. A. Patented [5]
PMID25522065-Compound-50 DMBWA0V N. A. N. A. Patented [5]
PMID25522065-Compound-12 DMVKO9C N. A. N. A. Patented [5]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Melanin-concentrating hormone receptor 1 (MCHR1) TTX4RTB MCHR1_HUMAN Antagonist [2]

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800021828)
2 Disruption of the melanin-concentrating hormone receptor 1 (MCH1R) affects thyroid function. Endocrinology. 2012 Dec;153(12):6145-54.
3 2011 Pipeline of Bristol-Myers Squibb.
4 Phase I clinical trial of AZD1979 for treating obesity. AstraZeneca plc
5 Novel MCH1 receptor antagonists: a patent review.Expert Opin Ther Pat. 2015 Feb;25(2):193-207.