Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMXY4BE)

Drug Name	PMID25991433-Compound-N2 Drug Info
Cross-matching ID	PubChem CID 46926710 TTD Drug ID DMXY4BE

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Patented Agent(s)

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Drug(s) Targeting Mitogen-activated protein kinase (MAPK)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
GBL-310	DM2IFJQ	Keratosis	ED56	Phase 2	[2]
LTT462	DM94E6W	Solid tumour/cancer	2A00-2F9Z	Phase 1	[3]
PF-07799544	DMAO10K	Aggressive cancer	2A00-2F9Z	Phase 1	[4]
PMID25991433-Compound-L2	DM58UO9	N. A.	N. A.	Patented	[1]
PMID25991433-Compound-L3	DM3LWUR	N. A.	N. A.	Patented	[1]
Bidentate ligands of Markush derivative 2	DM2QNMC	N. A.	N. A.	Patented	[5]
Bidentate ligands of Markush derivative 1	DMB08D3	N. A.	N. A.	Patented	[5]
PMID25991433-Compound-Q1	DMEMSB2	N. A.	N. A.	Patented	[1]
PMID25991433-Compound-C3	DMSKWBE	N. A.	N. A.	Patented	[1]
PMID25991433-Compound-J6	DMOWULJ	N. A.	N. A.	Patented	[1]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Mitogen-activated protein kinase (MAPK)	TTVOE6D	NOUNIPROTAC	Inhibitor	[1]

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References

1	c-Jun N-terminal kinase inhibitors: a patent review (2010 - 2014).Expert Opin Ther Pat. 2015;25(8):849-72.
2	WO patent application no. 2010,0456,51, Methods for analyzing drug response.
3	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
4	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2023. Adis Insight
5	Leucine-rich repeat kinase 2 inhibitors: a patent review (2014-2016).Expert Opin Ther Pat. 2017 Jun;27(6):667-676.