General Information of Drug (ID: DMXZGKI)

Drug Name
G009 Drug Info
Synonyms Beta-(1-3)-Glucan with beta-(1-6) side chain isolated from the Basidiomycetes Ganoderma lucidum
Indication
Disease Entry ICD 11 Status REF
Immune System disease 4A01-4B41 Investigative [1]
Cross-matching ID
TTD Drug ID
DMXZGKI

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Discontinued Drug(s)
Drug(s) Targeting Lipid peroxidation (LPO)
Drug Name Drug ID Indication ICD 11 Highest Status REF
T-817MA DMD72F4 Alzheimer disease 8A20 Phase 2 [2]
RAXOFELAST DMK2E0N Ischemia 8B10-8B11 Phase 2 [3]
TAK-218 DM7S69Q Neurological disorder 6B60 Discontinued in Phase 2 [4]
U-104067F DMC94D2 Neurological disorder 6B60 Discontinued in Phase 1 [5]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Lipid peroxidation (LPO) TTV0YFR NOUNIPROTAC Inhibitor [1]

References

1 Inhibition of lipid peroxidation and oxidative DNA damage by Ganoderma lucidum. Phytother Res. 2001 May;15(3):245-9.
2 A neuroprotective agent, T-817MA (1-{3-[2-(1-benzothiophen-5-yl)ethoxy]propyl} azetidin-3-ol maleate), prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in mice. Neuropharmacology. 2008 Oct;55(5):654-60.
3 Lipid peroxidation inhibition by raxofelast improves angiogenesis and wound healing in experimental burn wounds. Shock. 2005 Jul;24(1):85-91.
4 ESR study on the antioxidant activity of TAK-218 in biological model membranes. Chem Pharm Bull (Tokyo). 2000 Jun;48(6):784-92.
5 Two novel pyrrolopyrimidine lipid peroxidation inhibitors U-101033E and U-104067F protect facial motor neurons following neonatal axotomy. Exp Neurol. 1996 Oct;141(2):304-9.