Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMY7Q3I)

Drug Name

JNJ-10229570 Drug Info

Synonyms

JNJ-10229570-AAA; MC5R antagonist (topical, acne), Johnson & Johnson; Melanocortin-5 receptor antagonist (topical, acne), Johnson & Johnson

Indication

Disease Entry	ICD 11	Status	REF
Acne vulgaris	ED80	Phase 2	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Investigative Drug(s)

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Drug(s) Targeting Melanocortin receptor 5 (MC5R)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
MTC-896	DM7VG8L	Seborrhea	ED91.2	Phase 2	[3]
MT-II	DMKT1DA	Female sexual arousal dysfunction	HA01.1	Investigative	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	ClinicalTrials.gov (NCT01326780) A Study of a New Drug Treatment for Acne. U.S. National Institutes of Health.
2	A melanocortin receptor 1 and 5 antagonist inhibits sebaceous gland differentiation and the production of sebum-specific lipids. J Dermatol Sci. 2011 Jul;63(1):23-32.
3	Clinical pipeline report, company report or official report of Avarx.
4	The role of melanocortins in body weight regulation: opportunities for the treatment of obesity. Eur J Pharmacol. 2002 Apr 12;440(2-3):141-57.