General Information of Drug (ID: DMYAXNM)

Drug Name
SRK-015 Drug Info
Synonyms Apitegromab
Indication
Disease Entry ICD 11 Status REF
Spinal muscular atrophy 8B61 Phase 2 [1]
Cross-matching ID
TTD Drug ID
DMYAXNM

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Drug(s) Targeting Myostatin (MSTN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
AAV1-FS344 DMAPUZY Duchenne dystrophy 8C70 Phase 1/2 [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Myostatin (MSTN) TTM8I2X GDF8_HUMAN Inhibitor [2]

References

1 ClinicalTrials.gov (NCT03921528) An Active Treatment Study of SRK-015 in Patients With Type 2 or Type 3 Spinal Muscular Atrophy (TOPAZ). U.S. National Institutes of Health.
2 Clinical pipeline report, company report or official report of Scholar Rock.
3 Follistatin Gene Delivery Enhances Muscle Growth and Strength in Nonhuman Primates. Sci Transl Med. 2009 November 11; 1(6): 6ra15.