Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMYKXWE)

Drug Name

7beta, 25-dihydroxycholesterol Drug Info

Synonyms

CHEMBL3311219; (3S,7R,8S,9S,10R,13R,14S,17R)-17-[(2R)-6-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol; 7beta,25-dihydroxycholesterol; 7beta, 25-dihydroxycholesterol; AC1LAQHU; GTPL4355; SCHEMBL2485860; 7.beta.,25-Dihydroxycholesterol; BDBM50045543; (3.beta.,7.beta.)-7,25-Dihydroxycholest-5-en-3-ol

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 473142
TTD Drug ID: DMYKXWE

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

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Drug(s) Targeting EBV-induced G-protein coupled receptor 2 (GPR183)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
27-hydroxycholesterol	DM2L6OZ	Discovery agent	N.A.	Investigative	[2]
25-hydroxycholesterol	DMCHAQ7	Discovery agent	N.A.	Investigative	[2]
7alpha,25-dihydroxycholesterol	DM2N8TW	Discovery agent	N.A.	Investigative	[3]
7alpha,27-dihydroxycholesterol	DM52UOM	Discovery agent	N.A.	Investigative	[2]
7beta-hydroxycholesterol	DMPHJZU	Discovery agent	N.A.	Investigative	[2]
7beta, 27-dihydroxycholesterol	DMSDINR	Discovery agent	N.A.	Investigative	[2]
7alpha-hydroxycholesterol	DMH6LD0	Discovery agent	N.A.	Investigative	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
EBV-induced G-protein coupled receptor 2 (GPR183)	TTME5YJ	GP183_HUMAN	Agonist	[2]

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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4355).
2	Oxysterols direct B-cell migration through EBI2. Nature. 2011 Jul 27;475(7357):519-23.
3	Oxysterols direct immune cell migration via EBI2. Nature. 2011 Jul 27;475(7357):524-7.