Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMYM6FU)

Drug Name

ADX-914 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Atopic dermatitis	EA80	Phase 2	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Interleukin 7 receptor alpha (IL7R)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
CYT 99007	DMMWIHC	Acquired immune deficiency syndrome	1C62.3	Phase 2	[3]
PF-06342674	DMASKX9	Type-1 diabetes	5A10	Phase 1	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Interleukin 7 receptor alpha (IL7R)	TTAWI51	IL7RA_HUMAN	Antagonist	[2]

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References

1	ClinicalTrials.gov (NCT05509023) A Randomized, Double-Blind, Placebo-Controlled Phase 2a Proof-of-Concept Study Evaluating the Safety and Efficacy of ADX-914 in Subjects With Moderate to Severe Atopic Dermatitis. U.S.National Institutes of Health.
2	Clinical pipeline report, company report or official report of Q32bio
3	Perspectives on interleukin-7 therapy in HIV infection. Curr Opin HIV AIDS. 2007 May;2(3):228-33.
4	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)