Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMYOR5T)

Drug Name
CAR-T cells targeting CD133 Drug Info
Indication
Disease Entry ICD 11 Status REF
Acute myeloid leukaemia 2A60 Preclinical [1]
Cross-matching ID
TTD Drug ID
DMYOR5T

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Prominin-1 (PROM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Anti-CD133-CAR vector-transduced T cells DMGUM90 Brain cancer 2A00 Phase 1 [2]
ICT-121 DM64LVS Recurrent glioblastoma 2A00.00 Phase 1 [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Prominin-1 (PROM1) TTXMZ81 PROM1_HUMAN CAR-T-Cell-Therapy [1]

References

1 ClinicalTrials.gov (NCT03473457) CAR-T Cells Therapy in Relapsed/Refractory Acute Myeloid Leukemia
2 ClinicalTrials.gov (NCT02541370) Treatment of Relapsed and/or Chemotherapy Refractory Advanced Malignancies by CART133
3 Immunotargeting of cancer stem cells. Contemp Oncol (Pozn) 2015; 19(1A): A52-A59.