Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMYUL2X)

Drug Name
US9266828, E Drug Info
Synonyms SCHEMBL15289761; CHEMBL3936612; BDBM207842; US9266828, E
Cross-matching ID
PubChem CID
71722448
TTD Drug ID
DMYUL2X

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Patented Agent(s)
Preclinical Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Dibasic-processing enzyme (Furin)
Drug Name Drug ID Indication ICD 11 Highest Status REF
US9266828, C DMQEL1W N. A. N. A. Patented [1]
US9266828, B DMYUDCE N. A. N. A. Patented [1]
DecRVKRCMK DMAUILH Coronavirus infection 1D92 Preclinical [2]
furin inhibitor peptide DM78NOM Discovery agent N.A. Investigative [3]
peptide 18 DMIDP1R Discovery agent N.A. Investigative [4]
MI-1148 DMCN91V Discovery agent N.A. Investigative [5]
⏷ Show the Full List of 6 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Dibasic-processing enzyme (Furin) TTH9WF6 FURIN_HUMAN Inhibitor [1]

References

1 Inhibitors of Furin and other pro-protein convertases. US9266828.
2 Decanoyl-Arg-Val-Lys-Arg-Chloromethylketone: An Antiviral Compound That Acts against Flaviviruses through the Inhibition of Furin-Mediated prM Cleavage. Viruses. 2019 Oct 31;11(11):1011.
3 Targeting host cell furin proprotein convertases as a therapeutic strategy against bacterial toxins and viral pathogens. J Biol Chem. 2007 Jul 20;282(29):20847-53.
4 Design, synthesis, and structure-activity relationship studies of a potent PACE4 inhibitor. J Med Chem. 2014 Jan 9;57(1):98-109.
5 Novel Furin Inhibitors with Potent Anti-infectious Activity. ChemMedChem. 2015 Jul;10(7):1218-31.