Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMZ3QHF)

Drug Name

CB-102930 Drug Info

Synonyms

Antimicrobials, Cubist; CB-193; CB-286; CB-432; CB-447; CB-454; CB-484; CB-545; CB-628; CB-629; TRNA synthetase inhibitors (antimicrobial); TRNA synthetase inhibitors (antimicrobial), Cubist

Indication

Disease Entry	ICD 11	Status	REF
Bacterial infection	1A00-1C4Z	Terminated	[1]

Cross-matching ID

TTD Drug ID: DMZ3QHF

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Fungal Isoleucyl t-RNA synthetase (Fung ILS1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Icofungipen	DMTXNZK	Fungal infection	1F29-1F2F	Phase 2	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Fungal Isoleucyl t-RNA synthetase (Fung ILS1)	TTBZHDM	SYIC_YEAST	Inhibitor	[2]

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References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800016793)
2	Prospects for Aminoacyl-tRNA Synthetase Inhibitors as New Antimicrobial Agents. Antimicrob Agents Chemother. 2005 December; 49(12): 4821-4833.
3	Efficacy, plasma pharmacokinetics, and safety of icofungipen, an inhibitor of Candida isoleucyl-tRNA synthetase, in treatment of experimental disseminated candidiasis in persistently neutropenic rabbits. Antimicrob Agents Chemother. 2005 May;49(5):2084-92.