Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMZ5BHX)

Drug Name

PMID22123324C38 Drug Info

Synonyms

GTPL7757

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Melanin-concentrating hormone receptor 2 (MCHR2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
melanin-concentrating hormone	DMY57L0	Discovery agent	N.A.	Investigative	[2]
ATC0065	DMJNQ5G	Discovery agent	N.A.	Investigative	[3]
------------------------------------------------------------------------------------

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Melanin-concentrating hormone receptor 2 (MCHR2)	TTS17MG	MCHR2_HUMAN	Antagonist	[1]

------------------------------------------------------------------------------------

References

1	Discovery and characterization of a potent and selective antagonist of melanin-concentrating hormone receptor 2. Bioorg Med Chem Lett. 2012 Jan 1;22(1):363-6.
2	Identification and characterization of a second melanin-concentrating hormone receptor, MCH-2R. Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7564-9.
3	Anxiolytic- and antidepressant-like profile of ATC0065 and ATC0175: nonpeptidic and orally active melanin-concentrating hormone receptor 1 antagoni... J Pharmacol Exp Ther. 2005 May;313(2):831-9.