Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMZKEIH)

Drug Name

PMID25259874C4 Drug Info

Synonyms

GTPL8384; BDBM50028698

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

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Drug(s) Targeting C3a anaphylatoxin chemotactic receptor (C3AR1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
PMID25259874C21	DMTCGLY	Discovery agent	N.A.	Investigative	[1]
SB290157	DM28K0E	Discovery agent	N.A.	Investigative	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
C3a anaphylatoxin chemotactic receptor (C3AR1)	TTI6B3F	C3AR_HUMAN	Antagonist	[1]

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References

1	Potent heterocyclic ligands for human complement c3a receptor. J Med Chem. 2014 Oct 23;57(20):8459-70.
2	Identification of a selective nonpeptide antagonist of the anaphylatoxin C3a receptor that demonstrates antiinflammatory activity in animal models. J Immunol. 2001 May 15;166(10):6341-8.