General Information of Drug (ID: DMZKEIH)

Drug Name
PMID25259874C4 Drug Info
Synonyms GTPL8384; BDBM50028698
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
91827355
TTD Drug ID
DMZKEIH

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
PMID25259874C21 DMTCGLY Discovery agent N.A. Investigative [1]
SB290157 DM28K0E Discovery agent N.A. Investigative [2]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
C3a anaphylatoxin chemotactic receptor (C3AR1) TTI6B3F C3AR_HUMAN Antagonist [1]

References

1 Potent heterocyclic ligands for human complement c3a receptor. J Med Chem. 2014 Oct 23;57(20):8459-70.
2 Identification of a selective nonpeptide antagonist of the anaphylatoxin C3a receptor that demonstrates antiinflammatory activity in animal models. J Immunol. 2001 May 15;166(10):6341-8.