Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMZRW5E)

Drug Name

AGN211745 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Choroidal neovascularization	9B76	Discontinued in Phase 2	[1]

Therapeutic Class

siRNA

Cross-matching ID

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
VEGFR2 messenger RNA (VEGFR2 mRNA)	TTPFN62	VGFR2_HUMAN	Not Available	[2]

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References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800019725)
2	Teaming up to tackle RNAi delivery challenge. Nat Rev Drug Discov. 2009 Jul;8(7):525-6.