Details of the Drug Reposition

General Information of This Drug (ID: DM6KXAU)

• Drug Name: Dexpramipexole (DM6KXAU)
• Synonyms: Dexpramipexole; 104632-28-2; (R)-PRAMIPEXOLE; (R)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine; R-(+)-Pramipexole; (6R)-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine; WI638GUS96; KNS-760704; (6R)-N6-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine; Dexpramipexole [USAN:INN]; UNII-WI638GUS96; (R)-Pramipexole;R-(+)-Pramipexole;KNS-760704; Dexpramipexole (USAN/INN); DEXPRAMIPEXOLE [INN]; SCHEMBL74780; DEXPRAMIPEXOLE [USAN]; MLS006011813; CHEMBL249420; DEXPRAMIPEXOLE [WHO-DD]; DTXSID50146624; FASDKYOPVNHBLU-SSDOTTSWSA-N; BCP12512; 2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N6-propyl-, (6R)-; BDBM50568780; HY-17355B; AKOS005555111; CS-1196; DB15130; AC-36724; AS-56557; SMR004703492; D09886; EN300-123062; F19514; Q5268345; (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine; (R)-4,5,6,7-TETRAHYDRO-6-(PROPYLAMINO)-BENZOTHIAZOLE-2-AMINE; 2,6-BENZOTHIAZOLEDIAMINE, 4,5,6,7-TETRAHYDRO-N6-PROPYL-, (R)-
• Drug Type: Small molecule

Information on Drug Reposition of This Drug

1 Phase 3 Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Eosinophilic asthma	DISGAODP	CB02.0	Phase 3	[1]

1 Phase 2 Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Hypereosinophilic syndrome	DISVK62S	2A20.3	Phase 2	[2]

References

• [1] ClinicalTrials.gov (NCT05763121) A Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Assess the Efficacy, Safety, and Tolerability of Dexpramipexole Administered Orally for 52 Weeks in Participants With Severe Eosinophilic Asthma. U.S.National Institutes of Health.
• [2] ClinicalTrials.gov (NCT02101138) An Open-Label, Proof-of-Concept Study to Evaluate the Safety and Efficacy of Dexpramipexole (KNS-760704) in Subjects With Hypereosinophilic Syndrome. U.S.National Institutes of Health.