Details of the Drug Reposition | DrugMAP

General Information of This Drug (ID: DMT3D5I)

Drug Name	Aflibercept DMT3D5I
Synonyms	Ziv-Aflibercept; Zaltrap (TN); VEGF Trap; VEGF Trap-Eye

Information on Drug Reposition of This Drug

Molecular Interaction Atlas (MIA)

4 Approved Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Central retinal vein occlusion with macular edema	DISKBNZP	N.A.	Approved	[1]
Metastasis from malignant tumor of colon	DIS175N9	N.A.	Approved	[2]
Metastatic colorectal cancer	DIS18R3K	2B91	Approved	[3]
Exudative age-related macular degeneration	DIS88DJO	9B78.3Z	Approved	[4]
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References

1	A review of neovascular glaucoma. Etiopathogenesis and treatment. Rom J Ophthalmol. 2021 Oct-Dec;65(4):315-329.
2	A Comparison of Folinic Acid, Fluorouracil and Irinotecan (FOLFIRI) plus Bevacizumab and FOLFIRI plus Aflibercept as Second-line Treatment for Metastatic Colorectal Cancer. Clin Oncol (R Coll Radiol). 2022 Aug;34(8):e323-e328.
3	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
4	Efficacy and Safety of Intravitreal Aflibercept Treat-and-Extend Regimens in Exudative Age-Related Macular Degeneration: 52- and 96-Week Findings from ALTAIR : A Randomized Controlled Trial. Adv Ther. 2020 Mar;37(3):1173-1187.