Details of the Drug

General Information of Drug (ID: DM05MCO)

Drug Name

Inaperisone

Synonyms

Inapen; Inapene; Rilan; Riran; Inaperison HCl; Inaperisone hydrochloride; HN-770; HSR-770; HY-770; YM-170; YM-18170; 118230-97-]]]

Indication

Disease Entry	ICD 11	Status	REF
Pollakiuria	MF50.1	Discontinued in Preregistration	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

#Ro5 Violations (Lipinski): 0

Molecular Weight (mw)

245.36

Logarithm of the Partition Coefficient (xlogp)

3.4

Rotatable Bond Count (rotbonds)

5

Hydrogen Bond Donor Count (hbonddonor)

0

Hydrogen Bond Acceptor Count (hbondacc)

2

Chemical Identifiers

Formula: C16H23NO
IUPAC Name: 1-(4-ethylphenyl)-2-methyl-3-pyrrolidin-1-ylpropan-1-one
Canonical SMILES: CCC1=CC=C(C=C1)C(=O)C(C)CN2CCCC2
InChI: InChI=1S/C16H23NO/c1-3-14-6-8-15(9-7-14)16(18)13(2)12-17-10-4-5-11-17/h6-9,13H,3-5,10-12H2,1-2H3
InChIKey: VNFAARJCGSAROU-UHFFFAOYSA-N

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Nicotinic acetylcholine receptor (nAChR)	TTJSZTB	NOUNIPROTAC	Modulator	[2]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003120)
2	Inhibitory effect of inaperisone hydrochloride (inaperisone), a new centrally acting muscle relaxant, on the micturition reflex. Eur J Pharmacol. 1992 Mar 31;213(3):409-15.