Details of the Drug

General Information of Drug (ID: DM0JDCS)

• Drug Name: DBO-83
• Synonyms: DBO-83; EU-0100452; CHEMBL1527419; Tox21_500452; LP00452; CCG-221756; NCGC00261137-01; NCGC00093868-01; D 7938; SR-01000075832
• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight; 297.6
  Logarithm of the Partition Coefficient; Not Available
  Rotatable Bond Count; 1
  Hydrogen Bond Donor Count; 3
  Hydrogen Bond Acceptor Count; 4
• Chemical Identifiers:
  Formula: C10H15Cl3N4
  IUPAC Name: 3-(6-chloropyridazin-3-yl)-3,8-diazabicyclo[3.2.1]octane;dihydrochloride
  Canonical SMILES: C1CC2CN(CC1N2)C3=NN=C(C=C3)Cl.Cl.Cl
  InChI: InChI=1S/C10H13ClN4.2ClH/c11-9-3-4-10(14-13-9)15-5-7-1-2-8(6-15)12-7;;/h3-4,7-8,12H,1-2,5-6H2;2*1H
  InChIKey: FMBGHZXNKMHVDT-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 9926237
  CAS Number: 195211-53-1
  TTD ID: D0A4RM

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Nicotinic acetylcholine receptor (nAChR)	TTJSZTB	NOUNIPROTAC	Agonist	[1]

References

• [1] The therapeutic potential of nicotinic acetylcholine receptor agonists for pain control. Expert Opin Investig Drugs. 2001 Oct;10(10):1819-30.