Details of the Drug

General Information of Drug (ID: )

Drug Name
Synonyms
Indication
Disease Entry ICD 11 Status REF
Diabetic complication 5A2Y Approved [1]
#Ro5 Violations (Lipinski): 1 Molecular Weight (mw)
Logarithm of the Partition Coefficient (xlogp)
Rotatable Bond Count (rotbonds)
Hydrogen Bond Donor Count (hbonddonor)
Hydrogen Bond Acceptor Count (hbondacc)
Cross-matching ID

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Dipeptidyl peptidase 4 (DPP-4) TTDIGC1 DPP4_HUMAN Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Diabetic complication
ICD Disease Classification 5A2Y
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Dipeptidyl peptidase 4 (DPP-4) DTT DPP4 9.54E-01 -0.27 -1.85
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 KOMBIGLYZE XR tablets approved in the US for the treatment of type 2 diabetes mellitus in adults
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1612).