Details of the Drug

General Information of Drug (ID: DM0W64U)

Drug Name

Dihydropyridines

Synonyms

1,2-dihydropyridine; UNII-YA306KG67U; 22694-45-7; YA306KG67U; Pyridine, 1,2-dihydro-; AC1L8RRH; CTK1A1117; MMWRGWQTAMNAFC-UHFFFAOYSA-N; AKOS006352484; 27183-EP2311806A2; 27183-EP2308562A2; 27183-EP2301911A1; 27183-EP2292593A2; 27183-EP2314575A1; 27183-EP2295427A1; 27183-EP2270010A1; 27183-EP2269990A1; 27617-EP2270006A1; 27183-EP2371811A2; 27183-EP2308510A1; 27183-EP2295426A1; 27183-EP2275404A1; 27617-EP2314587A1; 27183-EP2292611A1; 27183-EP2284149A1

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

#Ro5 Violations (Lipinski): 0

Molecular Weight (mw)

81.12

Logarithm of the Partition Coefficient (xlogp)

1.1

Rotatable Bond Count (rotbonds)

0

Hydrogen Bond Donor Count (hbonddonor)

1

Hydrogen Bond Acceptor Count (hbondacc)

1

Chemical Identifiers

Formula: C5H7N
IUPAC Name: 1,2-dihydropyridine
Canonical SMILES: C1C=CC=CN1
InChI: InChI=1S/C5H7N/c1-2-4-6-5-3-1/h1-4,6H,5H2
InChIKey: MMWRGWQTAMNAFC-UHFFFAOYSA-N

Cross-matching ID

PubChem CID: 407038
CAS Number: 22694-45-7
TTD ID: D09TRN

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Voltage-gated L-type calcium channel (L-CaC)	TTXHYV6	NOUNIPROTAC	Blocker	[1]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	Pharmacology of N-type Ca2+ channels distributed in cardiovascular system (Review). Int J Mol Med. 1999 May;3(5):455-66.