Details of the Drug

General Information of Drug (ID: DM19FS3)

• Drug Name: Norzimelidine
• Synonyms: Norzimeldine; 3-(4-Bromophenyl)-N-methyl-3-(3-pyridinyl)-2-propen-1-amine; 2-Propen-1-amine, 3-(4-bromophenyl)-N-methyl-3-(3-pyridinyl)-; cholesterol-3-glucose; AC1O5OK9; CHEMBL173745; SCHEMBL11636758; 60324-58-5; LS-175771; A-23889; 3-(4-bromophenyl)-N-methyl-(3-pyiidyl)allylamine oxalate
• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 303.2
  Logarithm of the Partition Coefficient (xlogp); 3.4
  Rotatable Bond Count (rotbonds); 4
  Hydrogen Bond Donor Count (hbonddonor); 1
  Hydrogen Bond Acceptor Count (hbondacc); 2
• Chemical Identifiers:
  Formula: C15H15BrN2
  IUPAC Name: (Z)-3-(4-bromophenyl)-N-methyl-3-pyridin-3-ylprop-2-en-1-amine
  Canonical SMILES: CNC/C=C(/C1=CC=C(C=C1)Br)\\C2=CN=CC=C2
  InChI: InChI=1S/C15H15BrN2/c1-17-10-8-15(13-3-2-9-18-11-13)12-4-6-14(16)7-5-12/h2-9,11,17H,10H2,1H3/b15-8-
  InChIKey: AZFZKANGXPSDEA-NVNXTCNLSA-N
• Cross-matching ID:
  PubChem CID: 5378630
  CAS Number: 60324-59-6
  TTD ID: D0A0KE

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Monoamine uptake (MA uptake)	TTJXYQ6	NOUNIPROTAC	Inhibitor	[1]

References

• [1] The antidepressant agents desipramine, fluoxetine, fluvoxamine and norzimelidine inhibit uptake of [3H]noradrenaline and [3H]5-hydroxytryptamine in slices of human and rat cortical brain tissue. Brain Res. 1983 Sep 19;275(1):99-104.