Details of the Drug

General Information of Drug (ID: DM1V78I)

Drug Name

MK-6096

Synonyms

FILOREXANT; MK-6096; 1088991-73-4; UNII-E6BTT8VA5Z; MK6096; MK 6096; E6BTT8VA5Z; ((2R,5R)-5-(((5-Fluoropyridin-2-yl)oxy)methyl)-2-methylpiperidin-1-yl)(5-methyl-2-(pyrimidin-2-yl)phenyl)methanone; Methanone, [(2R,5R)-5-[[(5-fluoro-2-pyridinyl)oxy]methyl]-2-methyl-1-piperidinyl][5-methyl-2-(2-pyrimidinyl)phenyl]-; Methanone, ((2R,5R)-5-(((5-fluoro-2-pyridinyl)oxy)methyl)-2-methyl-1-piperidinyl)(5-methyl-2-(2-pyrimidinyl)phenyl)-; Filorexant [USAN:INN]; Filorexant (USAN); Filorexant(mk-6096); MK-6096; Filorexant; GTPL4460

Indication

Disease Entry	ICD 11	Status	REF
Diabetic neuropathy	8C0Z	Phase 2	[1]
Insomnia	7A00-7A0Z	Phase 2	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C24H25FN4O2
Canonical SMILES: CC1CCC(CN1C(=O)C2=C(C=CC(=C2)C)C3=NC=CC=N3)COC4=NC=C(C=C4)F
InChI: 1S/C24H25FN4O2/c1-16-4-8-20(23-26-10-3-11-27-23)21(12-16)24(30)29-14-18(6-5-17(29)2)15-31-22-9-7-19(25)13-28-22/h3-4,7-13,17-18H,5-6,14-15H2,1-2H3/t17-,18-/m1/s1
InChIKey: NPFDWHQSDBWQLH-QZTJIDSGSA-N

Cross-matching ID

PubChem CID: 25128145
CAS Number: 1088991-73-4
TTD ID: D0NN5A

Repurposed Drugs (RPD)

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References

1	ClinicalTrials.gov (NCT01021852) Polysomnography Study of MK6096 in Patients With Primary Insomnia (6096-011). U.S. National Institutes of Health.