Details of the Drug

General Information of Drug (ID: DM20B90)

Drug Name
AMT-130
Indication
Disease Entry ICD 11 Status REF
Huntington disease 8A01.10 Phase 1/2 [1]
Drug Type
Gene therapy
Cross-matching ID
TTD ID
D09ROP

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Huntingtin (HTT) TTUKLBM HD_HUMAN Not Available [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT05243017) A Phase Ib/II Study to Explore Safety, Tolerability, and Efficacy Signals of Multiple Ascending Doses of Striatally-Administered rAAV5-miHTT Total Huntingtin Gene (HTT) Lowering Therapy (AMT 130) in Early Manifest Huntington's Disease. U.S.National Institutes of Health.