Details of the Drug

General Information of Drug (ID: DM20EL1)

Drug Name

K-Ras(G12C) inhibitor 12

Synonyms

K-Ras(G12C) inhibitor 12; 1469337-95-8; 1-(4-(2-(4-chloro-2-hydroxy-5-iodophenylamino)acetyl)piperazin-1-yl)prop-2-en-1-one; 1-(4-(2-((4-Chloro-2-hydroxy-5-iodophenyl)amino)acetyl)piperazin-1-yl)prop-2-en-1-one; 1-(4-{2-[(4-chloro-2-hydroxy-5-iodophenyl)amino]acetyl}piperazin-1-yl)prop-2-en-1-one; K-Ras(G12C)inhibitor12; C15H17ClIN3O3; GTPL8020; SCHEMBL15337917; KS-00001DCR; MolPort-035-687-474; BCP23940; ZINC97756593; 2131AH; s7331; AKOS024258726; CS-5104; ACN-052937; NCGC00386405-01; HY-18707; BC600757; AJ-138489

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]
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Drug Type

Small molecular drug

Structure

3D MOL is unavailable

2D MOL

Chemical Identifiers

Formula: C15H17ClIN3O3
Canonical SMILES: C=CC(=O)N1CCN(CC1)C(=O)CNC2=CC(=C(C=C2O)Cl)I
InChI: 1S/C15H17ClIN3O3/c1-2-14(22)19-3-5-20(6-4-19)15(23)9-18-12-8-11(17)10(16)7-13(12)21/h2,7-8,18,21H,1,3-6,9H2
InChIKey: JFIFBWVNHLXJFY-UHFFFAOYSA-N

Cross-matching ID

PubChem CID: 73555129
TTD ID: D04QKN

References

1	K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions. Nature. 2013 Nov 28;503(7477):548-51.