Details of the Drug

General Information of Drug (ID: DM295IJ)

Drug Name

AR101

Synonyms

5-[[(2R)-2-Cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl]methyl]pyrimidine-2,4-diamine; (R)-Iclaprim; CHEMBL1236788; 5-[[(2R)-2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl]methyl]pyrimidine-2,4-diamine; 5-{[(2R)-2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl]methyl}pyrimidine-2,4-diamine; SCHEMBL20138534; CHEBI:131752; XCF; ZINC3612862; BDBM50336513; DB08741; UNII-42445HUU0O component HWJPWWYTGBZDEG-AWEZNQCLSA-N

Indication

Disease Entry	ICD 11	Status	REF
Allergy	4A80-4A85	Phase 3	[1]
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Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C19H22N4O3
Canonical SMILES: COC1=C(C2=C(C=CC(O2)C3CC3)C(=C1)CC4=CN=C(N=C4N)N)OC
InChI: 1S/C19H22N4O3/c1-24-15-8-11(7-12-9-22-19(21)23-18(12)20)13-5-6-14(10-3-4-10)26-16(13)17(15)25-2/h5-6,8-10,14H,3-4,7H2,1-2H3,(H4,20,21,22,23)/t14-/m0/s1
InChIKey: HWJPWWYTGBZDEG-AWEZNQCLSA-N

Cross-matching ID

PubChem CID: 10247560
ChEBI ID: CHEBI:131752
TTD ID: D0O8TJ

References

1	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)