General Information of Drug (ID: DM2JTS5)

Drug Name
Follitropin beta
Indication
Disease Entry ICD 11 Status REF
Female infertility GA31.Z Approved [1]
Therapeutic Class
Fertility Agents
Sequence
>Alpha chain
APDVQDCPECTLQENPFFSQPGAPILQCMGCCFSRAYPTPLRSKKTMLVQKNVTSESTCC
VAKSYNRVTVMGGFKVENHTACHCSTCYYHKS t="FASTA">>Beta chainNSCELTNITIAIEKEECRFCISINTTWCAGYCYTRD
LVYKDPARPKIQKTCTFKELVYETVRVPGCAHHADSLYTYPVATQCHCGKCDSDSTDCTV
RGLGPSYCSFGEMKE
Cross-matching ID
TTD ID
D0OM3A

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Follicle-stimulating hormone receptor (FSHR) TTZFDBT FSHR_HUMAN Binder [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Female infertility
ICD Disease Classification GA31.Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Follicle-stimulating hormone receptor (FSHR) DTT FSHR 1.56E-02 -0.56 -1.34
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77.
2 Follitropin-alpha (Gonal-F) versus follitropin-beta (Puregon) in controlled ovarian hyperstimulation for in vitro fertilization: is there any diffe... Fertil Steril. 2009 Apr;91(4 Suppl):1522-5.