General Information of Drug (ID: DM32AKH)

Drug Name
G-207 virus construct
Synonyms HrR3; G-207; G-47; G-47delta; G-207 virus construct, Catherex; G-207 virus construct, MediGene; HSV mutants (glioma), NCI; Oncolytic herpes simplex virus (glioma), Catherex/MediGene
Indication
Disease Entry ICD 11 Status REF
Glioma 2A00.0 Phase 1/2 [1]
Cross-matching ID
TTD ID
D0YU1M

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Ribonucleotide reductase (RIR) TTX09M4 RIR1_HUMAN ; RIR2_HUMAN ; RIR2B_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT00028158) Safety and Effectiveness Study of G207, a Tumor-Killing Virus, in Patients With Recurrent Brain Cancer. U.S. National Institutes of Health.
2 Anti-tumor effect of oncolytic herpes simplex virus G47delta on human nasopharyngeal carcinoma. Chin J Cancer. 2011 Dec;30(12):831-41.