Details of the Drug

General Information of Drug (ID: DM3CQIZ)

• Drug Name: TRIPHENYLMETHANAMINE
• Synonyms: Tritylamine; Triphenylmethanamine; 5824-40-8; Triphenylmethylamine; Benzenemethanamine, .alpha.,.alpha.-diphenyl-; BZVJOYBTLHNRDW-UHFFFAOYSA-N; tritylamin; trityl amine; NSC1154; Aminotriphenylmethane; Triphenylaminomethane; triphenyl methylamine; Triphenylmethanamine #; Aminotrityl, polymer-bound; Triphenylmethylamine, 99%; 1,1,1-triphenylmethanamine; Aminotrityl polystyrene resin; Methylamine,1,1-triphenyl-; KSC490G4B; SCHEMBL115149; ACMC-209m39; AC1Q506E; CHEMBL272255; AC1Q506F; BEN104; AC1L3D64; BDBM23786; Methylamine, 1,1,1-trip

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 259.3
  Logarithm of the Partition Coefficient (xlogp); 3.4
  Rotatable Bond Count (rotbonds); 3
  Hydrogen Bond Donor Count (hbonddonor); 1
  Hydrogen Bond Acceptor Count (hbondacc); 1
• Chemical Identifiers:
  Formula: C19H17N
  IUPAC Name: triphenylmethanamine
  Canonical SMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)N
  InChI: InChI=1S/C19H17N/c20-19(16-10-4-1-5-11-16,17-12-6-2-7-13-17)18-14-8-3-9-15-18/h1-15H,20H2
  InChIKey: BZVJOYBTLHNRDW-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 138598
  CAS Number: 5824-40-8
  TTD ID: D03FAG
  VARIDT ID: DR00734

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Calcium-activated potassium channel (KCN)	TTMNI76	NOUNIPROTAC	Inhibitor	[1]

References

• [1] Novel inhibitors of the Gardos channel for the treatment of sickle cell disease. J Med Chem. 2008 Feb 28;51(4):976-82.