Details of the Drug | DrugMAP

General Information of Drug (ID: DM3D0WA)

Drug Name	Amidox
Drug Type	Small molecular drug
Structure
Structure	3D MOL			2D MOL
#Ro5 Violations (Lipinski): 0	Molecular Weight (mw)			168.15
	Logarithm of the Partition Coefficient (xlogp)			0.8
	Rotatable Bond Count (rotbonds)			1
	Hydrogen Bond Donor Count (hbonddonor)			4
	Hydrogen Bond Acceptor Count (hbondacc)			4
Chemical Identifiers	Formula C7H8N2O3 IUPAC Name N',3,4-trihydroxybenzenecarboximidamide Canonical SMILES C1=CC(=C(C=C1/C(=N/O)/N)O)O InChI InChI=1S/C7H8N2O3/c8-7(9-12)4-1-2-5(10)6(11)3-4/h1-3,10-12H,(H2,8,9) InChIKey JOAASNKBYBFGDN-UHFFFAOYSA-N
Cross-matching ID	PubChem CID 135413522 CAS Number 95933-72-5 TTD ID D06PWA

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Ribonucleotide reductase (RIR)	TTX09M4	RIR1_HUMAN ; RIR2_HUMAN ; RIR2B_HUMAN	Inhibitor	[1]

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Molecular Interaction Atlas (MIA)

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References

1	Metabolism of the new ribonucleotide reductase inhibitor amidox in the isolated perfused rat liver. Anticancer Res. 2000 Sep- Oct;20(5B):3521-6.