Details of the Drug

General Information of Drug (ID: DM3LDFB)

Drug Name
Simoctocog alfa
Synonyms Factor VIII - Octapharma; Human-cl rhFVIII - Octapharma; Nuwiq
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
ADMET Property
Clearance
The clearance of drug is 2.96 +/- 0.97 mL/h/kg [2]
Half-life
The concentration or amount of drug in body reduced by one-half in 12.50 +/- 4.17 hours (in pediatric patients) [2]
Vd
The volume of distribution (Vd) of drug is 0.05975 L/kg [2]
Cross-matching ID
DrugBank ID
DB09108
TTD ID
D0B6EG

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Coagulation factor VIII (F8) TT1290U FA8_HUMAN Modulator [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Coagulation factor VIII (F8) DTT F8 1.08E-22 0.89 1.82
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 A new recombinant factor VIII: from genetics to clinical use
2 Nuwiq Product Monograph