Details of the Drug

General Information of Drug (ID: DM3O4ST)

Drug Name
SS1(dsFv)-PE38
Synonyms CAT-5001; SS (dsFv) PE38 immunotoxin); SS1-PE38; SS (dsFv) PE38 immunotoxin, NCI; SS1P, Enzon/NCI
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Discontinued in Phase 1 [1]
Drug Type
Antibody
Cross-matching ID
TTD ID
D09YUK

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Mesothelin (MSLN) TT4RXME MSLN_HUMAN Not Available [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Solid tumour/cancer
ICD Disease Classification 2A00-2F9Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Mesothelin (MSLN) DTT MSLN 2.86E-20 3.98 6.12
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800012262)
2 Mesothelin targeted cancer immunotherapy. Eur J Cancer. 2008 Jan;44(1):46-53.