Details of the Drug

General Information of Drug (ID: DM4HS92)

Drug Name

1-Methyl-5-(4-phenylazo-phenyl)-piperidin-2-one

Synonyms

CHEMBL56908; 1-Methyl-5-(4-phenylazo-phenyl)-piperidin-2-one; BDBM50091710; 1-Methyl-5-[(E)-azobenzene-4-yl]piperidine-2-one

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

#Ro5 Violations (Lipinski): 0

Molecular Weight (mw)

293.4

Logarithm of the Partition Coefficient (xlogp)

3.3

Rotatable Bond Count (rotbonds)

3

Hydrogen Bond Donor Count (hbonddonor)

0

Hydrogen Bond Acceptor Count (hbondacc)

3

Chemical Identifiers

Formula: C18H19N3O
IUPAC Name: 1-methyl-5-(4-phenyldiazenylphenyl)piperidin-2-one
Canonical SMILES: CN1CC(CCC1=O)C2=CC=C(C=C2)N=NC3=CC=CC=C3
InChI: InChI=1S/C18H19N3O/c1-21-13-15(9-12-18(21)22)14-7-10-17(11-8-14)20-19-16-5-3-2-4-6-16/h2-8,10-11,15H,9,12-13H2,1H3
InChIKey: GUDNFCRTZUCEOP-UHFFFAOYSA-N

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Steroid 5-alpha-reductase 1 (SRD5A1)	TTTU72V	S5A1_HUMAN	Inhibitor	[1]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	Simple bi- and tricyclic inhibitors of human steroid 5alpha-reductase. Bioorg Med Chem Lett. 2000 Sep 4;10(17):1909-11.