Details of the Drug

General Information of Drug (ID: DM4NMBW)

Drug Name
Anti-Mesothelin CAR-T cells
Indication
Disease Entry ICD 11 Status REF
Gastric adenocarcinoma 2B72 Phase 1/2 [1]
Mesothelioma 2C51.2 Phase 1/2 [1]
Pancreatic cancer 2C10 Phase 1/2 [1]
Solid tumour/cancer 2A00-2F9Z Phase 1 [2]
Drug Type
CAR T Cell Therapy
Cross-matching ID
TTD ID
D0BE6M
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Mesothelin (MSLN) TT4RXME MSLN_HUMAN CAR-T-Cell-Therapy [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT03638206) Autologous CAR-T/TCR-T Cell Immunotherapy for Malignancies
2 ClinicalTrials.gov (NCT03545815) Study of CRISPR-Cas9 Mediated PD-1 and TCR Gene-knocked Out Mesothelin-directed CAR-T Cells in Patients With Mesothelin Positive Multiple Solid Tumors.