Details of the Drug

General Information of Drug (ID: DM574C8)

Drug Name

Rintatolimid

Synonyms

Ampligen; Atvogen; Poly I:Poly C12U; POLYI-POLYC12U; Poly(I).poly(c12,U); Mismatched double-stranded RNA; Poly I-Poly C (C12,U); (rI(n).r(C(12)U)n); DRG-0001; Poly(inosinic acid) poly(cytidylic(12), uridylic)acid; 38640-92-5; 5'-Inosinic acid, homopolymer, complex with 5'-cytidylic acid polymer with 5'-uridylic acid (1:1); Poly(I)-Poly(C12U); Rintatolimod [USAN:INN]; UNII-94325AJ25N; SCHEMBL27306; AC1L1Z15; DTXSID50191952; 94325AJ25N; LS-174734; C10H13N4O8P.C9H13N2O9P.C9H14N3O8P; 1308845-87-5; 1221495-86-8

Indication

Disease Entry	ICD 11	Status	REF
Solid tumour/cancer	2A00-2F9Z	Phase 1/2	[1]
Chronic fatigue syndrome	8E49	Application submitted	[2]
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Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C28H40N9O25P3
Canonical SMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COP(=O)(O)O)O)O
InChI: 1S/C10H13N4O8P.C9H14N3O8P.C9H13N2O9P/c15-6-4(1-21-23(18,19)20)22-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17;10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18;12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h2-4,6-7,10,15-16H,1H2,(H,11,12,17)(H2,18,19,20);1-2,4,6-8,13-14H,3H2,(H2,10,11,15)(H2,16,17,18);1-2,4,6-8,13-14H,3H2,(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,10-;2*4-,6-,7-,8-/m111/s1
InChIKey: KNUXHTWUIVMBBY-JRJYXWDASA-N

Cross-matching ID

PubChem CID: 135537060
CAS Number: 38640-92-5
TTD ID: D0NE5B

Repurposed Drugs (RPD)

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References

1	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)