Details of the Drug

General Information of Drug (ID: DM5X76V)

Drug Name
Oligomycin C
Synonyms Ambotz11052-72-5; O5251_SIGMA; Oligomycin C; Q27107578; SCHEMBL454280; ZINC255967246; 11052-72-5; AB01209739-01; AC1NQZ9I; AKOS024418757; BRD-K05350981-001-01-0; C11313; MFCD00043231
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski): 2 Molecular Weight (mw) 775.1
Logarithm of the Partition Coefficient (xlogp) 8
Rotatable Bond Count (rotbonds) 3
Hydrogen Bond Donor Count (hbonddonor) 4
Hydrogen Bond Acceptor Count (hbondacc) 10
Chemical Identifiers
Formula
C45H74O10
IUPAC Name
(1S,4E,5'R,6R,6'R,7S,8R,10S,11R,12R,14R,15R,16S,18E,20E,22S,25R,27S,28R,29S)-22-ethyl-7,11,15-trihydroxy-6'-[(2S)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethylspiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-oxane]-3,9,13-trione
Canonical SMILES
CCC1CCC2C(C(C(C3(O2)CCC(C(O3)CC(C)O)C)C)OC(=O)C=CC(C(C(C(=O)C(C(C(C(=O)C(C(C(CC=CC=C1)C)O)C)C)O)C)C)O)C)C
InChI
CMMLZMMKTYEOKV-JEKNLLRFSA-N
InChIKey
1S/C45H74O10/c1-12-35-17-15-13-14-16-26(3)39(48)30(7)41(50)32(9)43(52)33(10)42(51)31(8)40(49)27(4)18-21-38(47)53-44-29(6)36(20-19-35)54-45(34(44)11)23-22-25(2)37(55-45)24-28(5)46/h13-15,17-18,21,25-37,39-40,43-44,46,48-49,52H,12,16,19-20,22-24H2,1-11H3/b14-13+,17-15+,21-18+/t25-,26+,27-,28+,29+,30-,31-,32+,33-,34-,35-,36-,37-,39-,40+,43-,44+,45-/m1/s1
Cross-matching ID
PubChem CID
5281901
CAS Number
11052-72-5
INTEDE ID
DR2638

Molecular Interaction Atlas of This Drug


Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 107W1 (cyp107)
Main DME 		DEV62G1 PIKC_STRVZ Substrate [1], [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 153 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 -10.7566 -5.5729 -10.7624 91.5395
MEC1 CTRP2 -6.6554 26.834 -16.6632 56.7047
JM1 CTRP2 -0.0619 59.2601 -26.4282 47.7944
697 CTRP2 -16.7586 0.446 -17.6706 84.8343
SUP-T11 CTRP2 -15.0509 15.0574 -20.2503 71.0512
THP-1 CTRP2; CTRP1 -14.7349 3.2316 -16.0725 80.4987
A4/Fukuda CTRP2 -14.7131 -0.3671 -15.3177 84.9102
SU-DHL-4 CTRP2; CTRP1 -14.4066 7.849 -17.007 75.6503
L-540 CTRP2 -14.3796 0.2827 -15.0692 83.8556
CMK CTRP2 -14.2608 15.3312 -19.5133 70.1701
OCI-Ly3 CTRP2 -13.9511 7.2427 -16.3255 75.7661
KYO-1 CTRP2 -13.7949 11.1513 -17.4561 72.4303
A3/Kawakami CTRP2 -13.7916 5.0141 -15.5037 77.7957
BV-173 CTRP2 -12.8249 2.1278 -13.745 80.2736
KHM-1B CTRP2 -12.6127 7.9993 -15.1063 73.7344
SU-DHL-6 CTRP2 -12.3563 2.1327 -13.237 79.8258
GA-10 CTRP2 -12.3236 2.4538 -13.2705 79.3769
MOLP-8 CTRP2 -12.1016 11.2222 -15.6557 70.5637
HL-60 CTRP2 -12.0989 20.5489 -19.3668 65.3768
Mono-Mac-1 CTRP2 -12.0799 6.8979 -14.1811 74.1511
BCP-1 CTRP2 -12.0431 -9.5989 -12.0431 98.9351
Mino CTRP2 -11.7188 10.4766 -14.9759 70.6593
SET-2 CTRP2 -11.699 26.632 -21.62 62.755
EoL-1 CTRP2 -11.5488 -10.0969 -11.5488 99.6162
DEL CTRP2 -11.383 -10.4405 -11.383 99.8969
Pfeiffer CTRP2 -11.3162 -6.7634 -11.3178 94.2147
MOLM-16 CTRP2; CTRP1 -11.235 -7.9708 -11.235 96.4943
BL-70 CTRP2; CTRP1 -11.1846 -10.0799 -11.1846 99.7161
KMS-12-BM CTRP2 -11.1259 -5.4445 -11.1359 91.5272
MOLT-16 CTRP2 -11.0498 -9.2842 -11.0498 98.7649
MHH-CALL-4 CTRP2 -10.966 -6.3999 -10.9679 93.3445
LP-1 CTRP2; CTRP1 -10.9507 17.948 -17.0672 65.2396
NALM-6 CTRP2 -10.7492 12.1658 -14.5512 68.2137
NB4 CTRP2 -10.5372 2.4401 -11.3265 77.3004
P3HR-1 CTRP2; CTRP1 -10.4693 11.1331 -13.8627 68.559
HH [Human lymphoma] CTRP2 -10.0685 20.6118 -17.2926 63.004
ST486 CTRP2 -9.8756 12.3646 -13.6922 66.8623
MC116 CTRP2; CTRP1 -9.8319 16.9982 -15.5005 64.2537
K-562 CTRP2 -9.5362 35.7138 -23.6586 58.4154
U-937 CTRP2; CTRP1 -9.5025 21.1763 -16.9513 62.0872
Ri-1 CTRP2 -9.3893 8.1035 -11.6377 69.2976
SR CTRP2 -9.3729 -8.3337 -9.3729 95.2588
CA46 CTRP2 -9.301 27.0856 -19.4084 60.0182
JVM-3 CTRP2 -9.0915 10.9958 -12.3365 66.5644
KMS-34 CTRP2 -9.0018 -1.0519 -9.148 80.3592
SU-DHL-8 CTRP2 -8.9822 18.5443 -15.277 62.383
AMO1 CTRP2; CTRP1 -8.8807 18.1528 -14.9983 62.412
KMS-21-BM CTRP2 -8.7232 -6.7124 -8.7232 90.326
CML-T1 CTRP2 -8.6606 9.5677 -11.3527 66.8634
L-363 CTRP2 -8.4158 16.2159 -13.6986 62.5422
Kasumi-1 CTRP2 -8.4098 26.9365 -18.4497 58.9844
MV4-11 CTRP2 -8.3579 -7.5027 -8.3579 89.247
Mono-Mac-6 CTRP2 -8.1136 34.1299 -21.5244 57.2088
DB CTRP2 -8.0982 16.4083 -13.4483 61.953
HPB-ALL CTRP2 -7.9889 9.4292 -10.5787 65.7263
P12-Ichikawa CTRP2 -7.8607 13.9069 -12.1616 62.7371
RCH-ACV CTRP2 -7.7134 12.6368 -11.4961 63.1506
Ku812 CTRP2; CTRP1 -7.6114 -5.7491 -7.6114 83.9894
L-428 CTRP2 -7.4683 22.0867 -15.2917 58.9771
F-36P CTRP2 -7.4677 12.594 -11.2185 62.7166
Peer CTRP2 -7.4594 -6.3189 -7.4594 83.2744
NCO2 CTRP2 -7.4361 -3.6526 -7.4386 80.779
TF-1 CTRP2 -7.4065 28.7788 -18.312 57.3284
OCI-AML-5 CTRP2 -7.3689 26.4555 -17.1925 57.7549
HT CTRP2; CTRP1 -7.2759 -5.7229 -7.2759 81.9933
GDM-1 CTRP2; CTRP1 -6.8284 11.3145 -10.0322 62.1693
Jurkat CTRP2 -6.459 -5.9225 -6.459 76.6372
KMS-26 CTRP2 -6.3914 12.5528 -10.0629 60.5761
EJM CTRP2; CTRP1 -6.3587 70.6955 -37.7007 52.7706
KE-37 CTRP2 -6.3424 13.6862 -10.4744 59.9554
JeKo-1 CTRP2 -6.3133 32.0605 -18.7969 55.4106
NU-DUL-1 CTRP2; CTRP1 -6.0786 1.9235 -6.4056 68.0758
NCI-H929 CTRP2 -5.902 7.9984 -7.8214 61.9886
RS4;11 CTRP2 -5.6417 21.3994 -13.1415 56.237
MOLT-13 CTRP2 -5.492 -2.078 -5.4955 69.641
SU-DHL-1 CTRP2 -5.4612 21.2296 -12.8831 55.9584
MM1.S CTRP2 -5.1992 16.913 -10.6729 56.4694
Kasumi-2 CTRP2 -4.8627 22.631 -12.9343 54.6471
MOLM-13 CTRP2 -4.7488 5.3977 -5.7418 60.115
JJN-3 CTRP2 -4.4361 23.4117 -12.8781 53.7795
RPMI-8226 CTRP2; CTRP1 -4.0535 38.3369 -19.6737 52.0465
M-07e CTRP2 -3.8844 10.842 -6.725 54.8041
LAMA-84 CTRP2 -3.7943 13.3103 -7.6576 53.9716
PL21 CTRP2; CTRP1 -3.6379 18.3744 -9.7439 52.8216
SU-DHL-5 CTRP1 -3.3651 -2.0198 -3.3651 99.1845
SUP-HD1 CTRP2 -3.3534 39.443 -19.5722 51.1316
KE-97 CTRP2; CTRP1 -3.3166 16.9526 -8.7732 52.2165
SUP-B15 CTRP2 -3.2807 54.3201 -26.8342 50.7766
SK-MM-2 CTRP2 -3.2167 12.1088 -6.5465 52.4736
EM-2 CTRP2 -3.0925 12.3122 -6.5033 52.0589
Daudi CTRP2 -2.9616 44.77 -21.83 50.5708
NOMO-1 CTRP2; CTRP1 -2.4873 7.8227 -4.0677 50.1496
JURL-MK1 CTRP2 -2.3707 13.5592 -6.2992 49.7148
Reh CTRP2 -2.0722 15.8408 -7.0231 48.8863
ALL-SIL CTRP2 -1.9699 6.0988 -2.9224 47.4817
SKM-1 CTRP1 -1.9554 10.7961 -4.6729 64.2981
OCI-AML-3 CTRP2; CTRP1 -1.8497 31.1113 -14.0937 49.0144
RPMI-8402 CTRP2 -1.6668 29.6802 -13.2328 48.6404
Karpas-299 CTRP2 -1.2175 16.4146 -6.4377 46.3925
ME1 CTRP2 -0.8025 17.207 -6.4015 45.2815
EB1 CTRP2 -0.6423 29.4018 -12.1467 46.7609
MHH-CALL-3 CTRP2 -0.542 47.6498 -21.0759 47.8354
MOLM-6 CTRP2 -0.4491 21.6209 -8.1726 45.2277
SEM CTRP2 -0.2583 16.1015 -5.3487 43.2122
KMS-18 CTRP2 -0.0673 36.6759 -15.2101 46.4865
OPM-2 CTRP2 0.0261 26.7798 -10.2443 45.0654
HDLM-2 CTRP2 0.0462 21.9245 -7.8529 44.0153
PF-382 CTRP2 0.1072 29.7913 -11.6512 45.3795
OCI-Ly19 CTRP2 0.1625 53.3054 -23.2662 47.3127
HEL CTRP2 0.4244 37.5089 -15.1823 45.8052
KM-H2 CTRP2 0.6649 22.3762 -7.4961 42.5058
HEL 92.1.7 CTRP2 0.8047 132.7539 -62.3769 48.6427
U266B1 CTRP2 0.8187 30.9183 -11.5634 44.1864
KMS-27 CTRP2 0.8479 123.8963 -57.9139 48.5256
Namalwa CTRP2 0.9668 71.0421 -31.4111 47.3281
TALL-1 [Human adult T-ALL] CTRP2 1.0901 7.2752 -0.0341 30.0946
MOLT-3 CTRP2 1.9359 29.6741 -9.9481 41.6186
SIG-M5 CTRP2 2.1829 41.9297 -15.8339 43.706
KCL-22 CTRP2 2.5446 30.8725 -10.0078 40.6669
SUP-M2 CTRP2 2.657 21.9853 -5.4896 36.5944
DND-41 CTRP2 2.668 18.9863 -3.9941 34.549
Granta-519 CTRP2 2.7557 46.7457 -17.7429 43.5964
AML-193 CTRP2 3.1845 4.9521 3.039 12.8974
Toledo CTRP2 3.3114 13.1355 -0.5228 25.4846
KMS-20 CTRP2 3.452 17.8353 -2.7222 30.5725
KMS-11 CTRP2; CTRP1 3.6181 32.7343 -9.997 39.0196
RL CTRP2 4.2782 45.6173 -15.884 41.2521
HuT 78 CTRP2 4.3119 5.8489 3.9399 6.2821
MJ CTRP2 4.352 9.9841 1.9762 14.2346
SUP-T1 CTRP2 4.4176 21.8766 -3.8996 30.7998
Ki-JK CTRP2 4.6571 22.9112 -4.2138 30.884
MOTN-1 CTRP2 4.865 7.0464 3.8902 5.2092
KMS-28BM CTRP2 4.974 8.5891 3.213 9.0594
OCI-AML-2 CTRP2 5.5144 24.2856 -4.1874 29.2964
Ci-1 CTRP2 5.5672 10.6107 2.684 8.9398
Karpas-620 CTRP2 5.662 9.8474 3.1362 6.9015
RPMI-6666 CTRP2 6.256 31.888 -7.3816 32.6629
P31/FUJ CTRP2 6.3957 33.8822 -8.2644 33.4426
HuNS1 CTRP2 6.8775 42.4714 -12.1642 36.2017
MOLP-2 CTRP2 7.1802 27.0593 -4.2377 26.6439
NU-DHL-1 CTRP2 7.3871 39.5872 -10.3156 34.1153
OCI-M1 CTRP2 7.5631 35.7125 -8.2446 31.8266
REC-1 CTRP2 7.6786 9.5027 4.4518 0.2269
Raji CTRP2 7.8333 15.6774 1.834 8.8036
Hs 611.T CTRP2 7.862 26.745 -3.5565 24.2906
WSU-DLCL2 CTRP2; CTRP1 7.8897 24.1914 -2.2628 22.3409
OCI-Ly10 CTRP2; CTRP1 7.9371 15.6681 1.9185 8.4166
HD-MY-Z CTRP2 7.9707 58.5896 -19.3303 38.9622
KO52 CTRP2 7.9813 26.6374 -3.4129 23.8173
BL-41 CTRP2 8.2306 31.1891 -5.4768 27.202
KMM-1 CTRP2 8.764 31.8453 -5.3965 26.3341
Karpas-422 CTRP2 10.6032 35.2464 -5.7118 24.4708
EHEB CTRP2 11.2634 33.5834 -4.4334 21.4226
⏷ Show the Full List of 153 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 0.8177 50.1631 -21.1273 46.3904
TE8 CTRP2 3.947 4.9271 3.8767 7.5544
EC-GI-10 CTRP2 -15.4982 15.9692 -21.0791 70.916
KYSE-30 CTRP2 -12.5505 14.3452 -17.3087 69.0108
KYSE-510 CTRP2 -11.7017 -9.7979 -11.7017 99.2697
TE-5 CTRP2 -3.4271 35.5776 -17.7515 51.3407
KYSE-140 CTRP2; CTRP1 -1.222 41.2902 -18.5249 48.429
OE21 CTRP2 1.3932 46.1561 -18.6282 45.3369
KYSE-410 CTRP2; CTRP1 1.6711 38.745 -14.6845 44.0162
TE-4 CTRP2 3.6328 5.8708 3.2196 10.9192
TE-6 CTRP2 6.4913 23.1669 -2.8411 24.9817
KYSE-150 CTRP2 6.7784 31.3007 -6.6681 31.014
TE-11 CTRP2 7.4407 66.765 -23.8424 40.9894
TE-9 CTRP2 7.5441 38.3901 -9.5938 33.2524
TE-14 CTRP2 8.2277 34.2454 -6.9954 29.4154
TE-10 CTRP2 8.667 24.4031 -1.8071 19.1023
TE-1 CTRP2 8.9534 35.4126 -7.0177 28.4914
KYSE-70 CTRP2 9.2399 30.666 -4.4602 24.0618
KYSE-520 CTRP2 9.6018 32.6922 -5.1897 24.87
KYSE-450 CTRP2; CTRP1 10.2411 89.6559 -33.0023 41.3386
OE33 CTRP2 10.536 32.9102 -4.6193 22.6637
OE19 CTRP2 11.5432 45.406 -10.0097 29.0659
KYSE-180 CTRP2 11.8087 42.7356 -8.5042 27.0486
COLO 680N CTRP2 12.8701 31.2282 -2.2422 14.9018
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 14.3606 59.7674 -14.9946 30.883
PSN1 CTRP2 -12.1258 -9.9921 -12.1258 99.3357
KP-4 CTRP2 -10.1582 35.9954 -24.3992 58.9681
HuP-T4 CTRP2; CTRP1 -9.4014 -7.7037 -9.4014 94.2215
L3.3 CTRP2 -6.9283 18.2134 -13.0165 59.3192
QGP-1 CTRP2; CTRP1 0.7829 24.3519 -8.3478 42.7995
Panc 10.05 CTRP2; CTRP1 0.9909 3.6716 0.9069 27.3586
MIA PaCa-2 CTRP2 1.7192 16.2699 -3.5338 36.0587
KP-3 CTRP2; CTRP1 2.1561 19.2368 -4.574 36.5455
HPAC CTRP2; CTRP1 2.5636 14.4085 -1.8294 30.7764
PaTu 8988s CTRP2 3.4811 53.7029 -20.5996 43.594
SU.86.86 CTRP2 3.7267 4.917 3.639 9.0827
PK-45H CTRP2 4.3167 52.5783 -19.3316 42.4186
DAN-G CTRP2 4.6841 9.0167 2.7505 10.3527
Panc 08.13 CTRP2 4.707 12.4126 1.0755 16.9924
PaTu 8902 CTRP2; CTRP1 5.766 7.0409 4.5767 1.0003
SNU-410 CTRP2 6.107 21.9247 -2.5274 24.9487
Panc 03.27 CTRP2; CTRP1 6.4184 105.9536 -44.2601 45.1305
Capan-1 CTRP2 6.6203 32.4967 -7.3916 32.1454
Hs 766T CTRP2 6.7293 16.9011 0.455 15.4469
TCC-Pan2 CTRP2 6.978 22.0995 -1.9302 22.039
SUIT-2 CTRP2; CTRP1 7.0102 26.438 -4.0512 26.6037
BxPC-3 CTRP2 7.2793 24.8706 -3.0733 24.1894
HuP-T3 CTRP2 7.4431 32.5054 -6.7418 30.1562
HPAF-II CTRP2 7.5259 36.6671 -8.7495 32.4245
SNU-213 CTRP2 7.6735 8.8375 4.6753 0.0246
CFPAC-1 CTRP2; CTRP1 8.4241 20.4771 -0.0577 14.5434
AsPC-1 CTRP2 8.4807 43.3923 -11.3465 33.7033
Panc 05.04 CTRP2 8.6216 32.718 -5.936 27.3777
SW1990 CTRP2 8.8209 46.0318 -12.3934 34.1678
PK-59 CTRP2 9.412 34.5215 -6.2314 26.7796
Capan-2 CTRP2; CTRP1 11.0932 38.4294 -6.9037 25.7389
YAPC CTRP2 11.4329 21.9252 1.1457 7.0553
Panc 02.03 CTRP2 12.2744 34.9211 -4.3826 20.1414
Panc 04.03 CTRP2 12.5979 31.3654 -2.4795 15.7563
PaTu 8988t CTRP2 13.1382 37.3791 -4.9767 20.2856
KP-2 CTRP2 16.4279 45.7947 -6.8044 20.0687
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 49 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 8.2399 22.9086 -1.3848 18.6281
WM88 CTRP2 -18.1802 14.4001 -23.3552 73.8819
UACC-62 CTRP2 -17.4381 0.9654 -18.5102 84.5214
Hs 944.T CTRP2; CTRP1 -12.4955 21.0469 -19.9852 65.5946
WM266-4 CTRP2 -11.4156 -9.8402 -11.4156 99.4062
G-361 CTRP2; CTRP1 -11.3537 7.3227 -13.5184 72.8778
CJM [Human melanoma] CTRP2 -11.2743 -3.5269 -11.3425 87.9026
WT2-iPS CTRP2 -11.2146 -3.7235 -11.272 88.2291
WM115 CTRP2 -9.7932 33.8435 -23.0304 59.0233
SK-MEL-1 CTRP2; CTRP1 -9.5706 55.6562 -33.2697 55.934
SK-MEL-5 CTRP2; CTRP1 -9.4163 7.2384 -11.3831 70.1379
SK-MEL-28 CTRP2; CTRP1 -9.3711 -9.098 -9.3711 96.0351
SK-MEL-31 CTRP2 -6.0806 13.2208 -10.0076 59.6043
LOX-IMVI CTRP2 -1.3952 87.0311 -41.4317 49.3401
WM983B CTRP2 -0.4751 420.2586 -207.18 49.7408
RVH-421 CTRP2 0.492 39.8277 -16.2729 45.9448
UACC-257 CTRP2 0.5613 123.9953 -58.207 48.6575
Malme-3M CTRP2 0.7416 46.8137 -19.5262 46.2294
COLO 792 CTRP2 0.7793 31.574 -11.9234 44.3782
SK-MEL-3 CTRP2 1.7317 35.9482 -13.2482 43.4344
COLO 741 CTRP1 1.8295 4.147 1.7352 46.4034
Hs 895.T CTRP2 4.395 5.0885 4.3231 4.5796
A-375 CTRP2; CTRP1 4.4232 19.8175 -2.8566 28.8588
RPMI-7951 CTRP2 4.4715 5.1807 4.3773 4.1534
Hs 940.T CTRP2 4.4978 5.1836 4.4048 3.9745
IGR-37 CTRP2 4.5364 5.0904 4.4768 3.5947
Hs 688(A).T CTRP2 4.595 4.9283 4.5801 3.0449
Hs 839.T CTRP2 4.6689 5.0003 4.6458 2.5814
Hs 852.T CTRP2; CTRP1 4.9259 20.8166 -2.9311 28.0302
SK-MEL-2 CTRP2 5.4404 7.2743 4.2398 2.6901
IGR-1 CTRP2 5.7573 7.8543 4.18 2.4659
IPC-298 CTRP2 6.886 8.7908 4.3932 0.6521
A2058 CTRP2 6.9059 7.9032 4.726 0.0496
IGR-39 CTRP2 7.253 8.456 4.6601 0.064
A101D CTRP2 7.5401 8.5886 4.7123 0.017
MDA-MB-435S CTRP2 9.5556 28.729 -3.2812 21.2926
MeWo CTRP2 9.7613 38.8231 -8.0931 28.8738
WM793 CTRP2 10.0155 19.7986 1.2831 8.0701
SK-MEL-24 CTRP2 10.128 26.7064 -1.8986 17.3202
COLO 829 CTRP2 10.4087 27.6662 -2.1684 17.6238
Mel JuSo CTRP2 10.7033 25.5506 -0.9632 14.125
Hs 936.T CTRP2; CTRP1 11.0168 21.0208 1.326 6.9476
K029AX CTRP2 11.0216 59.9991 -17.6244 35.4492
Mel Ho CTRP2 11.464 25.0365 -0.2432 11.2013
HT-144 CTRP2 11.5427 42.5065 -8.5856 27.4385
HMCB CTRP2 11.9511 71.3945 -22.5651 37.0658
COLO 800 CTRP2 12.3634 34.0278 -3.8951 19.0842
WM1799 CTRP2 14.7319 32.4176 -1.6602 11.6373
Hs 294T CTRP2 15.5026 35.4701 -2.5892 13.0771
⏷ Show the Full List of 49 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 CTRP2 -9.9219 21.7519 -17.6403 62.3972
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IMR-32 CTRP2 -13.9888 10.8083 -17.5444 72.8705
Kelly CTRP2 -8.0831 6.9105 -9.8319 67.9834
KP-N-SI9s CTRP2 -7.7981 24.0182 -16.5001 58.9198
NH-6 CTRP2 -2.3563 48.4494 -23.0971 49.8882
SK-N-BE(2) CTRP2 -0.6499 93.2762 -43.9023 48.9439
NB1 CTRP2 -0.0142 23.8991 -8.8714 44.613
SK-N-DZ CTRP2 2.746 12.7806 -0.8737 27.8734
CHP-126 CTRP2 3.1359 17.1552 -2.6668 31.1637
CHP-212 CTRP2 3.5609 46.6201 -16.9923 42.4678
SK-N-AS CTRP2 4.2986 5.088 4.2182 5.2514
MHH-NB-11 CTRP2 4.3497 37.4689 -11.7503 39.106
SK-N-FI CTRP2 5.253 7.0964 4.1866 3.2226
SiMa CTRP2 5.426 18.0347 -1.1356 22.7195
KP-N-YN CTRP2 6.1473 10.8761 2.9887 6.7224
SK-N-SH CTRP2 10.8993 40.6178 -8.13 27.5897
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-478 CTRP2 -8.9596 7.7696 -11.0611 68.8601
SNU-1079 CTRP2 -5.7251 18.0837 -11.7286 58.3193
HuCC-T1 CTRP2 1.7196 28.5697 -9.5923 41.78
SNU-308 CTRP2 7.4335 29.9876 -5.4964 28.3784
HuH-28 CTRP2 8.6524 30.4301 -4.7814 25.4481
SNU-869 CTRP2 9.4343 27.8225 -2.9258 20.6833
SNU-1196 CTRP2 10.5716 32.8704 -4.5746 22.5366
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-N-MC CTRP2 -16.2667 16.9868 -22.2938 70.9943
MG-63 CTRP2 -11.8357 -9.5648 -11.8357 98.9556
HOS CTRP2 -11.7692 -10.1343 -11.7692 99.5792
U2OS CTRP2; CTRP1 -11.4099 12.1742 -15.2581 69.0739
MHH-ES-1 CTRP2 -2.8426 33.9845 -16.4291 50.5603
CAL-78 CTRP2 1.7475 18.4109 -4.5523 37.4141
Hs 888.T CTRP2 4.3794 5.062 4.3138 4.6606
Hs 822.T CTRP2 4.6457 4.9504 4.6308 2.7072
SJSA-1 CTRP2 5.0196 7.4551 3.8183 5.2017
SK-ES-1 CTRP2 5.4213 36.0454 -10.1431 36.5269
TC71 CTRP2 6.4379 32.6874 -7.6337 32.6896
A-673 CTRP2 8.8777 34.0132 -6.3826 27.6993
SaOS-2 CTRP2 9.0986 44.1684 -11.2501 32.9226
SW1353 CTRP2 9.1993 29.2994 -3.8187 22.8881
G-292 clone A141B1 CTRP2 10.5823 46.3777 -11.208 31.2722
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 73 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC1500 CTRP2 -16.0943 12.8126 -20.531 73.3247
ZR-75-30 CTRP2 -12.8802 4.3669 -14.3364 77.6399
MDA-MB-468 CTRP2 -12.7162 32.8957 -25.4877 61.9829
MDA-MB-453 CTRP2 -11.6861 28.6143 -22.5007 62.1569
HCC2218 CTRP2 -9.5539 -7.6081 -9.5539 94.3806
MDA-MB-361 CTRP2 -8.0791 34.314 -21.5781 57.1411
HCC1419 CTRP2 -5.7624 40.7572 -22.4602 53.8508
CAL-148 CTRP2 -5.0426 15.5182 -9.9006 56.5152
DU4475 CTRP2 -2.6425 25.8956 -12.3199 50.3406
CAL-51 CTRP2 -2.299 47.488 -22.57 49.8233
UACC-812 CTRP2 -0.7422 239.0733 -116.8266 49.6065
AU565 CTRP2 -0.4518 26.6524 -10.6236 46.0578
Hs 578T CTRP2 -0.2522 43.0443 -18.532 47.2343
SK-BR-3 CTRP2 0.054 38.1721 -15.8424 46.4377
MDA-MB-157 CTRP2 0.1085 62.9278 -28.107 47.7677
MCF-7 CTRP2; CTRP1 0.9188 18.6443 -5.4314 40.3584
BT-474 CTRP2 1.3308 74.9817 -33.0652 47.1869
CAMA-1 CTRP2 2.138 23.217 -6.5648 38.7769
EFM-192A CTRP2 3.699 45.1374 -16.134 42.0089
Hs 578Bst CTRP2 4.4219 13.0643 0.5046 19.6519
HCC1428 CTRP2 4.4891 47.1304 -16.4631 41.2471
HCC202 CTRP2 4.5491 46.4919 -16.0935 41.0328
HCC1806 CTRP2 4.5888 20.7591 -3.1958 29.1708
CAL-120 CTRP2 4.7259 5.3847 4.5683 2.715
HMC-1-8 CTRP2 5.2023 45.8418 -15.2229 39.9202
HCC1395 CTRP2 5.8328 50.9506 -17.2551 40.143
MDA-MB-415 CTRP2 5.9707 27.1846 -5.2636 30.2797
HCC1954 CTRP2 7.1997 34.3115 -7.8341 31.8499
MDA-MB-231 CTRP2 7.2154 12.7653 2.8086 5.9219
HCC1143 CTRP2 7.2621 22.6755 -1.998 21.7413
BT-20 CTRP2 7.4496 76.779 -28.8387 42.2475
HDQ-P1 CTRP2 7.471 10.0398 4.1629 0.9207
T-47D CTRP2 7.8647 59.9085 -20.0742 39.356
ZR-75-1 CTRP2 8.6913 21.6872 -0.4686 15.3624
BT-549 CTRP2 9.5178 42.3935 -10.0456 31.3246
KPL-1 CTRP2 10.149 35.546 -6.1896 25.7847
HCC1937 CTRP2 10.6184 39.5985 -7.836 27.537
HCC38 CTRP2 11.1498 31.8764 -3.6873 20.091
CAL-85-1 CTRP2 11.3993 32.8051 -3.9632 20.3464
JIMT-1 CTRP2 12.8002 29.7028 -1.5769 13.3514
BT 239 CTRP2 -11.4642 -4.6232 -11.495 90.1221
BT 330 CTRP2 -10.6804 21.9059 -18.4862 63.2504
BT 271 CTRP2 -10.167 8.5243 -12.6219 70.1488
BT 231 CTRP2 -10.0797 9.921 -13.0096 68.8851
BT 145 CTRP2 -9.8285 15.9556 -15.0703 64.7462
BT 216 CTRP2 -8.0738 29.888 -19.4875 57.9303
BT164 CTRP2 -7.3793 34.1421 -20.8183 56.3882
BT 416 CTRP2 -7.3241 13.3097 -11.3535 62.0691
BT 245 CTRP2 -6.4258 17.9763 -12.3971 58.52
BT 248 CTRP2 -4.2257 10.0917 -6.7897 56.0834
BT147 CTRP2 -2.6228 13.334 -6.4586 50.5131
BT 504 CTRP2 -2.1185 27.1359 -12.4202 49.374
BT 112 CTRP2 -1.8599 40.596 -18.7689 49.2324
BT 286 CTRP2 -1.2931 11.826 -4.4329 45.6767
BT 172 CTRP2 -0.7356 49.8082 -22.3197 48.1425
BT 444 CTRP2 -0.3953 9.7213 -2.5985 40.8331
BT 422 CTRP2 0.0764 104.1094 -48.6867 48.6635
BT 232 CTRP2 0.1078 514.9192 -254.0184 49.726
BT 131 CTRP2 0.1182 7.5521 -1.1767 36.4265
BT 228 CTRP2 0.3131 41.5072 -17.2659 46.3562
BT 498 CTRP2 0.8895 33.3712 -12.7149 44.4753
BT 428 CTRP2 0.9594 3.8103 0.8526 27.576
BT 359 CTRP2 1.4594 24.6417 -7.8818 41.1738
BT 139 CTRP2 1.5049 1.9295 1.5049 23.5808
BT 440 CTRP2 1.8318 3.9713 1.7624 21.6379
BT 333 CTRP2 2.0656 66.191 -28.0454 46.1515
BT 482 CTRP2 2.7771 10.7457 0.138 24.7521
BT 340 CTRP2 3.3745 48.2599 -17.9702 42.9842
BT 159 CTRP2 6.935 24.2198 -3.0169 24.6235
BT 328 CTRP2 9.0828 27.5419 -3.0421 21.4278
BT 179 CTRP2 9.8356 27.423 -2.4472 19.0425
BT 320 CTRP2 10.6655 27.2484 -1.7947 16.3706
BT 224 CTRP2 14.287 40.8995 -5.8888 20.6604
⏷ Show the Full List of 73 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 42 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
T98G CTRP2 -11.8359 -8.5499 -11.8359 97.4911
8-MG-BA CTRP2 -11.8319 -10.1203 -11.8319 99.5475
U-251MG CTRP2 -11.5062 -6.6445 -11.5087 94.0462
GB-1 CTRP2 -11.4997 -9.826 -11.4997 99.3642
SF126 CTRP2 -11.4195 -7.9803 -11.4196 96.5285
KNS-42 CTRP2 -11.3398 -7.9759 -11.3399 96.5132
TM-31 CTRP2 -8.4724 -6.6648 -8.4724 89.2242
U-87MG ATCC CTRP2 -6.9923 -6.287 -6.9923 80.1902
YH-13 CTRP2 -6.4589 101.0411 -52.8479 52.0379
SNU-466 CTRP2 -4.8487 21.6752 -12.4773 54.778
D283 Med CTRP2 -2.956 17.8602 -8.8331 51.2425
SNU-489 CTRP2 -0.3671 7.0678 -1.5156 38.9167
DBTRG-05MG CTRP2 -0.2112 8.8754 -2.0534 39.3389
Daoy CTRP2 -0.0078 230.0674 -111.7044 49.4146
KNS-60 CTRP2 3.1584 3.8815 3.1562 12.5722
SF295 CTRP2; CTRP1 3.3631 60.1131 -23.8938 44.4323
KNS-81 CTRP2 3.6284 3.96 3.6283 9.4339
ONS-76 CTRP2 3.7123 71.6025 -29.3511 45.046
GaMG CTRP2; CTRP1 4.4101 17.8323 -1.8763 26.7066
CAS-1 CTRP2 4.4812 23.5371 -4.6753 31.9514
YKG-1 CTRP2 4.6283 13.7118 0.3592 19.7162
KG-1-C CTRP2 4.8866 5.4136 4.7161 1.7182
SW1783 CTRP2 5.1476 6.8546 4.2238 3.2554
SF268 CTRP2 5.3183 26.6123 -5.5122 31.7227
KALS-1 CTRP2 6.5594 53.5463 -17.9559 39.7094
LN-18 CTRP2 6.5989 7.6402 4.7071 0.1166
LN-229 CTRP2; CTRP1 7.6301 21.691 -1.2238 19.1799
U-118MG CTRP2 7.7981 25.8331 -3.1537 23.5518
A-172 CTRP2 7.9829 63.0372 -21.5411 39.8011
SNU-201 CTRP2 8.0834 35.2713 -7.6171 31.1794
SF539 CTRP2 8.8802 37.8402 -8.2768 30.1715
SW1088 CTRP2 9.3394 29.0141 -3.5768 22.2062
SNB-75 CTRP2 10.0591 39.1971 -8.0541 28.4704
Becker CTRP2 10.4364 61.3031 -18.7274 36.5311
Hs 683 CTRP2 11.1319 30.535 -3.0538 18.7663
SNU-1105 CTRP2 11.7956 35.1339 -4.8132 21.4963
DK-MG CTRP2 11.8514 46.363 -10.2529 29.002
GOS-3 CTRP2 11.9672 70.29 -22.0038 36.8178
42-MG-BA CTRP2 12.3404 38.8841 -6.2483 23.3057
M059K CTRP2 13.8742 46.9957 -9.106 25.6618
CCF-STTG1 CTRP2 14.673 44.3562 -7.2817 22.4416
GMS-10 CTRP2 15.5106 48.4282 -8.6666 23.5492
⏷ Show the Full List of 42 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-1 CTRP2 -16.3011 11.0323 -20.1226 74.7028
MFE-319 CTRP2; CTRP1 -15.0486 2.899 -16.3351 81.0912
HEC-151 CTRP2; CTRP1 -12.0856 6.5072 -14.0661 74.551
HEC-50B CTRP2 -11.585 -6.4984 -11.5885 93.7905
HEC-265 CTRP2; CTRP1 -7.5068 -6.9798 -7.5068 83.6337
HEC-1-A CTRP2 -5.2097 53.9743 -28.4158 52.5329
RL95-2 CTRP2 -2.8558 38.7689 -18.7824 50.5147
HEC-1-B CTRP2 -0.1973 40.2692 -17.1067 46.973
HEC-59 CTRP2; CTRP1 -0.0205 17.9143 -5.9726 43.075
JHUEM-3 CTRP2 0.116 113.9403 -53.5631 48.7589
JHUEM-2 CTRP1 2.0869 8.2935 0.5907 45.8536
HEC-6 CTRP1 2.1509 12.9055 -1.4901 47.1005
AN3-CA CTRP2 3.8146 48.6928 -17.8129 42.4616
KLE CTRP2; CTRP1 4.9712 53.3443 -19.157 41.7258
JHUEM-7 CTRP2 5.0108 37.858 -11.3904 37.9954
HEC-108 CTRP1 5.0724 45.5637 -15.1822 45.2617
ESS-1 CTRP2 5.6437 48.219 -16.0455 39.8152
HEC-251 CTRP1 6.0738 19.781 -1.4744 33.0464
MFE-296 CTRP2 10.2055 41.9618 -9.3094 29.7698
EN CTRP2 13.8304 35.1294 -3.4581 16.5924
Ishikawa (Heraklio) 02 ER- CTRP2; CTRP1 -7.3389 -7.0302 -7.3389 82.5164
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1272 CTRP2 -6.5523 60.9746 -33.089 53.3071
UO-31 CTRP2 -0.6537 42.0485 -18.3972 47.7056
TUHR14TKB CTRP2 0.6486 19.0351 -5.8834 52.6536
786-O CTRP2 2.8566 66.0083 -27.2793 45.4138
TUHR10TKB CTRP2 3.698 4.8979 3.6123 9.2668
RCC10RGB CTRP2; CTRP1 4.5957 8.0721 3.1507 8.9523
BFTC-909 CTRP2 4.5996 5.1793 4.5164 3.2624
KMRC-2 CTRP2 4.6481 5.0467 4.6113 2.7692
CAL-54 CTRP2 5.2396 28.9811 -6.7617 33.4852
KMRC-1 CTRP2 6.8885 15.7046 1.1621 12.6877
KMRC-3 CTRP2 6.893 9.3351 4.1734 1.285
TUHR4TKB CTRP2 7.1059 8.2745 4.6703 0.0727
VMRC-RCW CTRP2; CTRP1 7.1362 25.8501 -3.6603 25.6585
769-P CTRP2 7.1565 31.2783 -6.3566 30.044
A-498 CTRP2 8.5936 37.4509 -8.3043 30.5623
Caki-1 CTRP2 8.6346 46.7847 -12.9144 34.7608
OS-RC-2 CTRP2 9.3581 21.4971 0.0757 12.7817
KMRC-20 CTRP2 9.7369 26.8889 -2.2574 19.4964
VMRC-RCZ CTRP2 12.7502 43.2564 -8.0827 25.505
Caki-2 CTRP2 16.1063 44.9626 -6.6203 20.0781
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 53 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LS123 CTRP2; CTRP1 -16.7589 13.508 -21.4954 73.4082
GP2d CTRP2; CTRP1 -16.5877 4.266 -18.353 80.6303
SNU-C1 CTRP2 -14.3569 1.0724 -15.1916 82.8125
CW-2 CTRP2; CTRP1 -12.7693 5.506 -14.5215 76.313
SW620 CTRP2; CTRP1 -12.0757 -9.9859 -12.0757 99.3463
SNU-407 CTRP2 -10.4137 16.0699 -15.7325 65.4746
RKO CTRP2; CTRP1 -9.4673 -8.3557 -9.4673 95.614
SW1417 CTRP2 -8.3581 50.1341 -29.4548 55.48
CCK-81 CTRP2 -8.2239 2.4532 -8.8194 73.2851
SW480 CTRP1 -8.1933 1.5509 -8.619 89.2718
SNU-175 CTRP2; CTRP1 -8.0545 -1.5219 -8.1259 82.0652
LoVo CTRP2; CTRP1 -5.1834 16.6063 -10.5154 56.535
NCI-H747 CTRP2 -4.9024 55.503 -28.8883 52.2053
SW948 CTRP2; CTRP1 -3.584 28.3101 -14.3721 51.9038
COLO 320 CTRP2; CTRP1 -3.4369 40.9765 -20.3928 51.2023
SNU-C5 CTRP2; CTRP1 -3.1865 9.6077 -5.4904 52.7706
HT-55 CTRP2; CTRP1 -2.6888 39.6013 -19.0291 50.3019
SNU-C4 CTRP2; CTRP1 -2.5465 6.29 -3.6072 50.4536
LS513 CTRP2; CTRP1 -1.3245 25.8668 -11.0483 47.7884
SNU-61 CTRP2; CTRP1 -0.4453 34.4821 -14.4587 46.9032
LS180 CTRP2; CTRP1 -0.2715 36.4342 -15.2658 46.7929
LS411N CTRP2; CTRP1 0.7884 2.7058 0.7755 28.4661
SK-CO-1 CTRP2; CTRP1 0.8556 16.1909 -4.3065 39.3242
SNU-1033 CTRP2 0.8753 95.7423 -43.824 48.0742
NCI-H716 CTRP2 1.0683 66.5929 -29.103 47.0605
HCT 15 CTRP2 1.2858 75.6382 -33.4316 47.2462
KM12 CTRP2; CTRP1 1.395 69.3163 -30.172 46.9068
SNU-1040 CTRP1 1.491 13.2938 -2.3107 50.3051
C2BBe1 CTRP2; CTRP1 1.541 15.5006 -3.3212 36.2155
SNU-81 CTRP1 1.7628 21.0844 -5.843 49.4278
DLD-1 CTRP2; CTRP1 1.9034 3.7057 1.8691 21.1175
SW48 CTRP2; CTRP1 2.3313 11.3863 -0.5902 28.2109
CL-34 CTRP1 2.6576 12.0745 -0.6072 43.9529
T84 CTRP2 3.2598 7.5729 2.0997 16.301
LS1034 CTRP2 3.6529 39.1042 -13.1585 40.7985
NCI-H508 CTRP2; CTRP1 4.3293 18.7712 -2.4144 28.1102
HCT 8 CTRP2; CTRP1 4.6402 16.0321 -0.7804 23.337
CL-40 CTRP1 4.7196 6.6557 3.9627 11.3742
SW1116 CTRP2 4.7569 11.2619 1.6929 14.5162
SNU-C2A CTRP2; CTRP1 5.21 45.4688 -15.0203 39.8296
CL-11 CTRP2 5.5743 17.8936 -0.9442 21.9013
MDST8 CTRP2; CTRP1 6.0818 14.3434 1.2391 13.8248
SW403 CTRP1 6.5321 60.2827 -21.3351 44.9433
COLO205 CTRP2; CTRP1 7.0274 31.537 -6.5776 30.5596
HT-29 CTRP2; CTRP1 7.0353 8.3219 4.6431 0.1311
HCT 116 CTRP2; CTRP1 7.0494 8.6813 4.519 0.3279
OUMS-23 CTRP2 7.4283 18.7113 0.0815 15.5484
HT115 CTRP2; CTRP1 8.0048 21.8964 -1.0488 18.1117
COLO201 CTRP2 8.3137 35.6296 -7.6164 30.0976
SNU-503 CTRP2 8.5825 38.0451 -8.608 30.9222
COLO 678 CTRP2; CTRP1 8.6907 40.1512 -9.56 31.8271
HCC-56 CTRP2 10.424 35.2244 -5.8309 24.8831
RCM-1 [Human ESC] CTRP2; CTRP1 13.2352 37.6127 -5.0116 20.2765
⏷ Show the Full List of 53 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-5 CTRP2 -17.8216 4.952 -19.8848 80.6754
JHH-2 CTRP2 -17.6877 -1.8911 -18.2722 87.9109
JHH-4 CTRP2 -16.4188 12.6593 -20.825 73.6817
SNU-398 CTRP2; CTRP1 -12.901 15.2517 -18.0306 68.8671
PLC/PRF/5 CTRP2 -11.8793 -9.7672 -11.8793 99.18
SNU-886 CTRP2 -9.8889 16.6312 -15.4127 64.4943
HuH-6 CTRP2 -9.5618 15.9998 -14.8083 64.351
Hep 3B2.1-7 CTRP2 -3.6158 4.5563 -4.278 55.8699
Li-7 CTRP2 -0.5117 32.8376 -13.7165 46.8577
SNU-182 CTRP2 3.8014 12.3625 0.304 21.7146
JHH-6 CTRP2; CTRP1 4.4261 5.8606 4.0575 5.6093
SNU-761 CTRP2 4.9834 26.3194 -5.644 32.4737
HLF CTRP2 5.5382 20.4743 -2.263 25.3686
Hep-G2 CTRP2; CTRP1 5.6691 38.5392 -11.1756 37.0032
SNU-449 CTRP2; CTRP1 6.1174 27.875 -5.4795 30.3996
SNU-423 CTRP2 8.0156 37.9348 -8.995 32.054
SNU-475 CTRP2 8.1481 16.264 1.7624 8.6472
HuH-1 CTRP2 8.7473 18.6171 1.0403 10.421
SNU-387 CTRP2 9.7795 35.8247 -6.5998 26.8562
JHH-1 CTRP2 13.3544 56.0973 -13.9311 30.9268
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 162 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VMRC-LCD CTRP2; CTRP1 -16.1325 6.1009 -18.3607 78.5827
NCI-H1581 CTRP2 -15.5635 5.4317 -17.5526 78.7986
NCI-H211 CTRP2 -15.2436 1.0703 -16.1518 83.3514
NCI-H1975 CTRP2; CTRP1 -14.9974 0.8263 -15.8358 83.5245
DMS 273 CTRP2; CTRP1 -14.4789 12.28 -18.5945 72.2994
EPLC-272H CTRP2; CTRP1 -14.0325 20.8514 -21.5032 67.1848
NCI-H146 CTRP2 -13.8951 0.0301 -14.5034 83.9004
COLO 668 CTRP2; CTRP1 -13.5843 19.3788 -20.4201 67.4247
SW1573 CTRP2 -13.545 -3.9834 -13.6648 89.8436
NCI-H1755 CTRP2; CTRP1 -12.7498 8.6047 -15.4485 73.3692
NCI-H1694 CTRP2; CTRP1 -11.7671 26.2204 -21.4987 62.9618
KNS-62 CTRP2; CTRP1 -11.6756 -7.921 -11.6758 96.4397
NCI-H524 CTRP2 -11.6042 4.7361 -13.0415 75.8342
NCI-H2029 CTRP2; CTRP1 -11.1809 13.5286 -15.5282 67.9101
NCI-H1155 CTRP2 -11.1165 13.0521 -15.2807 68.1149
COR-L88 CTRP2; CTRP1 -10.9934 31.8899 -23.3003 60.6428
RERF-LC-MS CTRP2 -10.5277 62.0969 -37.3107 56.0459
COR-L279 CTRP2; CTRP1 -10.4843 7.3111 -12.5684 71.7144
EBC-1 CTRP2; CTRP1 -9.5414 12.8996 -13.5375 66.0458
SK-LU-1 CTRP2; CTRP1 -9.4648 -8.7352 -9.4648 96.2242
NCI-H1105 CTRP2; CTRP1 -8.9208 27.0814 -19.0195 59.5805
NCI-H1092 CTRP2 -8.8201 26.3948 -18.6106 59.6232
NCI-H841 CTRP2; CTRP1 -8.4596 32.8617 -21.2551 57.8161
NCI-H1341 CTRP2 -8.4551 28.9504 -19.4267 58.5787
Lu-65 CTRP2; CTRP1 -8.1769 29.5578 -19.4278 58.1296
NCI-H2106 CTRP2 -7.6732 18.2933 -13.817 60.5164
NCI-H1563 CTRP2 -7.5907 40.5343 -24.0828 55.7733
NCI-H1703 CTRP2 -7.5831 63.3976 -35.2247 53.9382
NCI-H889 CTRP2 -7.5587 5.2562 -8.7682 68.4649
SBC-5 CTRP2 -7.5071 -6.8736 -7.5071 83.6192
NCI-H460 CTRP2; CTRP1 -6.887 -5.1203 -6.887 79.3934
DMS 114 CTRP2 -6.7051 44.1346 -24.9868 54.5338
NCI-H1568 CTRP2; CTRP1 -5.5876 13.4064 -9.5618 58.4564
NCI-H1184 CTRP2 -5.4189 14.2708 -9.7542 57.7428
DMS 53 CTRP2 -5.4067 17.1632 -10.9956 56.8261
DMS 454 CTRP2 -5.3707 138.1159 -70.3583 51.1126
Calu-6 CTRP2; CTRP1 -5.3106 11.6521 -8.5534 58.508
HCC1833 CTRP2; CTRP1 -4.932 32.8627 -17.8481 53.5403
NCI-H82 CTRP1 -4.174 3.9479 -4.7371 81.1475
NCI-H810 CTRP2; CTRP1 -3.8159 24.539 -12.796 52.5651
LCLC-97TM1 CTRP2; CTRP1 -3.6606 19.8286 -10.436 52.7098
SCLC-21H CTRP2; CTRP1 -3.5985 7.8793 -5.2859 54.6854
NCI-H1944 CTRP2; CTRP1 -3.5703 21.4494 -11.1009 52.3651
HCC2108 CTRP2; CTRP1 -3.5137 60.087 -29.8896 50.9105
NCI-H1963 CTRP1 -3.4939 1.0835 -3.5615 88.9286
DV-90 CTRP2; CTRP1 -3.3381 30.7738 -15.3262 51.397
NCI-H69 CTRP2 -3.1377 36.0327 -17.7039 50.9355
NCI-H661 CTRP2; CTRP1 -3.1047 58.2955 -28.6354 50.5791
Lu-99 CTRP2; CTRP1 -1.3331 3.1345 -1.5013 42.9221
NCI-H1781 CTRP1 -1.0815 55.1195 -25.2563 52.5744
PC-14 CTRP2 -1.0414 15.4084 -5.7959 45.6314
NCI-H209 CTRP2 -0.6248 18.7522 -6.9621 45.1032
HCC33 CTRP1 -0.622 3.4559 -0.7882 71.7709
SHP-77 CTRP2; CTRP1 -0.4444 31.194 -12.8373 46.594
NCI-H1793 CTRP2; CTRP1 -0.3444 950.1354 -471.9896 49.8781
IA-LM CTRP2 -0.249 128.3636 -61.0801 49.0568
ChaGo-K-1 CTRP2; CTRP1 -0.2322 36.3288 -15.1783 46.7229
NCI-H1930 CTRP1 -0.1509 5.2869 -0.6906 64.5054
NCI-H1299 CTRP2; CTRP1 -0.0542 10.7063 -2.6645 39.8165
A-549 CTRP2; CTRP1 0.0174 17.1723 -5.5816 42.6956
HARA [Human squamous cell lung carcinoma] CTRP2; CTRP1 0.0849 35.17 -14.3193 46.1054
NCI-H1437 CTRP1 0.3141 5.915 -0.376 60.4577
NCI-H1836 CTRP1 0.5056 10.5559 -2.0256 55.4705
COR-L51 CTRP2; CTRP1 0.5143 34.5059 -13.6045 45.3097
NCI-H1395 CTRP2 0.5984 72.8737 -32.643 47.6867
HCC4006 CTRP2; CTRP1 0.7789 180.192 -86.0994 49.0112
HCC15 CTRP2; CTRP1 0.9465 29.8604 -10.9162 43.7428
COR-L105 CTRP2 0.9678 53.5111 -22.6647 46.4508
NCI-H1048 CTRP1 0.982 7.3015 -0.1545 54.4626
NCI-H522 CTRP2; CTRP1 1.0294 20.8511 -6.4037 40.9644
NCI-H526 CTRP2 1.0733 22.022 -6.9449 41.2698
NCI-H2172 CTRP2; CTRP1 1.1733 27.6811 -9.6338 42.7677
LXF 289 CTRP2; CTRP1 1.251 37.5528 -14.4612 44.511
NCI-H446 CTRP2 1.5009 34.4378 -12.7006 43.5629
NCI-H2196 CTRP2 1.5999 70.3293 -30.5112 46.7746
NCI-H1876 CTRP1 1.6663 27.2983 -9.0009 49.7716
NCI-H2073 CTRP1 1.7473 20.5022 -5.5706 49.4557
NCI-H2171 CTRP2 1.7641 6.5416 0.9676 24.6832
LCLC-103H CTRP2; CTRP1 1.8209 6.6565 0.9891 24.5102
HCC1195 CTRP2; CTRP1 1.8881 27.4363 -8.8709 41.0705
HCC44 CTRP2; CTRP1 1.8912 28.9599 -9.6242 41.5267
BEN CTRP2; CTRP1 1.9018 3.5109 1.8824 21.0775
NCI-H2126 CTRP2; CTRP1 2.1894 4.2245 2.1094 19.3705
NCI-H3255 CTRP1 2.1926 19.9758 -4.905 48.0735
NCI-H1373 CTRP2; CTRP1 2.2633 4.9444 2.0384 19.3892
CAL-12T CTRP2; CTRP1 2.272 7.9319 0.9388 23.4056
COR-L47 CTRP2 2.3392 59.2801 -24.3595 45.4145
DMS 79 CTRP2 2.4535 37.4687 -13.3744 42.4864
NCI-H596 CTRP1 2.4856 6.7421 1.662 40.5828
NCI-H1792 CTRP1 2.5326 5.3222 2.2257 37.8846
NCI-H1693 CTRP2 2.5939 5.7895 2.135 17.9725
NCI-H1573 CTRP2; CTRP1 2.6669 4.3624 2.6003 16.1467
COLO 699 CTRP2; CTRP1 2.8633 37.8657 -13.2083 41.8787
NCI-H1666 CTRP2; CTRP1 2.9214 4.9801 2.7472 14.8331
NCI-H23 CTRP2; CTRP1 3.0488 35.6187 -11.9268 41.0105
NCI-H2081 CTRP2; CTRP1 3.0509 7.0953 2.1049 16.9025
NCI-H2087 CTRP2 3.0998 4.9142 2.9563 13.4541
Calu-3 CTRP2; CTRP1 3.1922 23.3296 -5.6752 35.7885
NCI-H1734 CTRP2 3.302 19.9721 -3.9169 33.0638
NCI-H520 CTRP2 3.4144 32.411 -10.0199 39.3233
NCI-H2228 CTRP2 3.45 5.5835 3.1322 11.7668
NCI-H2009 CTRP2; CTRP1 3.4548 33.0887 -10.3142 40.3161
NCI-H727 CTRP2; CTRP1 3.5346 28.5682 -7.989 37.5732
HOP-62 CTRP2 3.5346 40.6669 -14.0402 41.3602
NCI-H1435 CTRP2; CTRP1 3.704 9.3431 1.7043 16.8543
COR-L95 CTRP2 3.8607 54.1297 -20.4915 43.1958
NCI-H647 CTRP2 4.0931 20.9587 -3.7188 31.1159
NCI-H2141 CTRP2; CTRP1 4.1229 21.1638 -3.7863 31.2126
SW1271 CTRP2 4.1641 5.1043 4.0667 6.2073
Sq-1 CTRP2; CTRP1 4.2355 21.7421 -3.9785 31.3227
LOU-NH91 CTRP2 4.2598 5.0514 4.1863 5.4844
NCI-H2444 CTRP2 4.3216 5.1658 4.2194 5.1784
EKVX CTRP2 4.3776 38.3613 -12.1729 39.3223
RERF-LC-KJ CTRP1 4.3952 15.5716 -0.7603 36.8857
NCI-H1915 CTRP2; CTRP1 4.3993 4.9589 4.3637 4.5124
NCI-H226 CTRP2 4.4082 5.0177 4.3572 4.4163
NCI-H2030 CTRP1 4.4134 14.5852 -0.2523 35.6729
NCI-H2286 CTRP2; CTRP1 4.5267 43.6678 -14.6908 40.4632
HCC1359 CTRP1 4.5757 4.9897 4.5487 7.1019
Calu-1 CTRP2 4.5821 15.4591 -0.5531 22.7349
NCI-H1355 CTRP2; CTRP1 4.7477 33.8969 -9.6202 37.0732
NCI-H2085 CTRP2 4.761 37.3006 -11.3205 38.2806
COR-L23 CTRP1 4.7857 5.3749 4.64 5.0832
HCC827 CTRP2; CTRP1 5.1791 23.539 -4.0811 29.7405
HCC1588 CTRP2 5.4305 38.6617 -11.4436 37.4835
NCI-H358 CTRP2; CTRP1 5.6216 30.649 -7.2703 33.5099
HCC78 CTRP2; CTRP1 5.8013 29.0042 -6.3008 32.0452
SK-MES-1 CTRP2 6.181 22.8243 -2.917 25.677
RERF-LC-Ad1 CTRP2 6.2443 7.1656 4.7419 0.1553
NCI-H2342 CTRP2; CTRP1 6.3619 44.6812 -13.6771 37.8022
NCI-H2122 CTRP2; CTRP1 6.8331 26.7861 -4.3638 27.4504
NCI-H1838 CTRP2 6.8923 9.7808 3.9811 1.9206
LK2 CTRP2 6.9194 49.6059 -15.6937 38.2956
NCI-H1869 CTRP2 7.1164 22.1814 -1.8645 21.6458
LC-1/sq-SF CTRP2; CTRP1 7.1485 73.5946 -27.4835 42.1674
RERF-LC-Ad2 CTRP2 7.2079 16.5841 0.9632 12.899
NCI-H441 CTRP2; CTRP1 7.3309 15.7438 1.471 10.9322
NCI-H2405 CTRP2; CTRP1 7.7264 22.9262 -1.7608 20.4508
HCC2935 CTRP2; CTRP1 8.1153 25.0701 -2.5278 21.7194
T3M-10 CTRP2; CTRP1 8.304 53.4904 -16.5085 37.3443
NCI-H838 CTRP2 8.5326 62.0279 -20.5952 38.9826
HCC2279 CTRP2 8.8292 38.6604 -8.723 30.7453
NCI-H2023 CTRP2; CTRP1 9.063 22.8006 -0.7373 15.6791
HOP-92 CTRP2 9.4524 34.1833 -6.0345 26.4287
HCC1171 CTRP2 9.4695 60.3337 -19.0045 37.4962
NCI-H2110 CTRP2; CTRP1 9.546 31.8447 -4.8033 24.3058
NCI-H2291 CTRP2 9.8117 24.5869 -1.0961 15.6246
MOR/CPR CTRP2 9.8379 19.9237 1.1186 8.8153
NCI-H1623 CTRP2 9.8531 26.4059 -1.9429 17.7936
NCI-H2170 CTRP2 9.8849 26.3624 -1.8999 17.6436
NCI-H650 CTRP2; CTRP1 10.2329 31.271 -4.0254 21.9567
HCC366 CTRP2 10.2781 25.2242 -1.0878 14.9978
NCI-H1650 CTRP2 10.7274 32.3399 -4.2062 21.6458
NCI-H1651 CTRP2 11.2978 47.4954 -11.2217 30.5394
HCC95 CTRP2 11.4201 30.512 -2.8479 17.9584
LUDLU-1 CTRP2 11.431 34.1791 -4.6049 21.5429
NCI-H1339 CTRP2 11.5313 59.3308 -16.9004 34.5908
NCI-H292 CTRP2 11.6352 31.2404 -3.0516 18.1549
NCI-H322 CTRP2 13.7783 37.4825 -4.601 18.9133
HCC1438 CTRP2 13.8988 33.0159 -2.4317 14.2673
NCI-H196 CTRP2 15.0097 44.4718 -7.1104 21.8621
Hs 888.Lu CTRP2 10.3183 33.6886 -5.1557 23.8926
⏷ Show the Full List of 162 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
P-STS CTRP2 -15.092 7.1985 -17.5549 76.795
SYO-1 CTRP2 -0.2012 14.5992 -4.5881 42.4388
H-STS CTRP2 7.5703 22.4197 -1.6385 20.3341
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 -6.2745 18.3676 -12.4152 58.1278
Aska-SS CTRP2 7.3548 33.636 -7.3745 31.0885
TE 617.T CTRP2 -14.5517 16.8335 -20.4123 69.6043
SK-LMS-1 CTRP2 -13.7579 -1.9091 -14.0783 86.636
SK-UT-1 CTRP2 -11.8428 -5.4456 -11.8604 91.8756
HT-1080 CTRP2; CTRP1 -11.5169 -9.834 -11.5169 99.3681
Rh41 CTRP2 -10.1283 4.6127 -11.3981 75.5232
KYM-1 CTRP2 -9.4289 4.577 -10.6256 72.9113
TE 441.T CTRP2 -9.184 14.4379 -13.773 64.608
G-401 CTRP2; CTRP1 -8.8266 13.3677 -12.9616 64.6611
RKN CTRP2; CTRP1 -8.3468 -7.9252 -8.3468 89.2242
TTC-709 CTRP2 -4.8588 7.6824 -6.5835 59.1234
G-402 CTRP2 -3.3466 34.324 -17.0655 51.2713
A-204 CTRP2 1.1405 35.5627 -13.5789 44.384
Rh18 CTRP2 2.2282 6.2616 1.57 21.1337
Tm87-16 CTRP2 4.2851 8.2024 2.7952 11.0253
MES-SA CTRP2 4.6247 60.56 -23.0639 43.1351
BT-16 CTRP2 5.7703 7.2642 4.4653 1.3384
SW982 CTRP2 5.954 7.1266 4.628 0.5941
GCT CTRP2 7.6447 34.2109 -7.4325 30.7621
RD CTRP2 7.8522 48.7355 -14.5076 36.6553
BT-12 CTRP2 8.2038 37.4505 -8.6069 31.3976
Hs 729.T CTRP2 14.6473 52.3362 -11.1551 27.2317
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 6.2813 41.2816 -12.0541 36.8398
A2780 CTRP2; CTRP1 -16.9766 0.2202 -17.8618 85.1942
JHOM-1 CTRP2; CTRP1 -16.7162 9.8595 -20.17 75.8816
OV56 CTRP2 -13.4012 32.6513 -26.0618 62.6352
TYK-nu CTRP2; CTRP1 -11.6076 -9.0091 -11.6076 98.2467
TOV-21G CTRP2 -11.3313 -9.4051 -11.3313 98.8837
COV434 CTRP2; CTRP1 -10.3918 3.7827 -11.4723 75.379
MCAS CTRP2 -9.6665 -8.3917 -9.6665 96.1966
HEY A8 CTRP2; CTRP1 -8.4269 -8.0523 -8.4269 89.7577
ES2 CTRP2 -7.5646 -7.1008 -7.5646 84.0029
OVK18 CTRP2; CTRP1 -3.8245 44.1582 -22.3112 51.5538
DOV13 CTRP2 -2.9573 33.8819 -16.4862 50.7284
OV-90 CTRP2; CTRP1 -0.3555 272.2886 -133.0943 49.5775
RMUG-S CTRP1 -0.2398 11.1814 -3.0638 58.2644
IGROV-1 CTRP2; CTRP1 -0.2058 128.2866 -60.9954 49.0406
OVCAR-4 CTRP2; CTRP1 1.6064 15.4588 -3.239 35.9176
TOV-112D CTRP2 1.784 55.8359 -23.1171 45.7298
OVKATE CTRP1 1.8877 13.9314 -2.2347 48.5495
OVCAR-8 CTRP2; CTRP1 1.977 12.4587 -1.4433 31.396
SNU-119 CTRP2 3.3656 11.0445 0.5516 21.888
OVMANA CTRP1 4.1998 5.4248 4.001 13.8177
COV318 CTRP1 4.2418 5.319 4.0847 12.8837
JHOS-4 CTRP1 4.2928 19.2165 -2.668 40.2757
OAW42 CTRP2; CTRP1 4.3241 4.8585 4.3015 4.9673
OV7 CTRP2; CTRP1 4.7045 21.2236 -3.3207 29.2296
COV362 CTRP2; CTRP1 4.947 6.5912 4.1976 3.8383
Caov-3 CTRP2; CTRP1 6.3801 27.6864 -5.1736 29.5161
SNU-8 CTRP2 6.9764 44.7679 -13.2311 37.4562
OVSAHO CTRP2 7.0092 9.5935 4.1234 1.3509
OVCAR-5 CTRP2 7.0663 36.5596 -9.0615 33.3476
FU-OV-1 CTRP2 7.1442 32.128 -6.7898 30.6437
RMG-I CTRP2; CTRP1 7.2417 24.4422 -2.8792 23.8708
ONCO-DG-1 CTRP2 7.6588 36.7753 -8.6984 32.1972
OAW28 CTRP2 8.6163 32.4436 -5.8042 27.1827
SK-OV-3 CTRP2; CTRP1 9.087 15.9564 2.4881 5.0199
OC 314 CTRP2 9.7508 37.9742 -7.6817 28.369
JHOC-5 CTRP2; CTRP1 10.1375 20.7969 0.9117 9.2069
OVISE CTRP2 10.3818 31.7447 -4.1614 21.9948
COV644 CTRP2; CTRP1 10.7314 36.6018 -6.2713 25.2282
EFO-27 CTRP2; CTRP1 10.7904 50.8792 -13.2676 32.8229
JHOS-2 CTRP2 11.0551 28.2694 -2.0216 16.4552
Kuramochi CTRP2 11.6933 38.4799 -6.5083 24.4351
OVTOKO CTRP2 12.8689 32.6028 -2.8872 16.3847
SNU-840 CTRP2; CTRP1 13.4234 47.0234 -9.427 26.5136
EFO-21 CTRP2; CTRP1 13.8694 54.9602 -12.9843 29.6935
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 6.6674 12.968 2.3402 8.5327
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H CTRP2; CTRP1 -12.5036 6.7513 -14.5951 74.7824
NCI-H2452 CTRP2 2.6987 12.5857 -0.8236 27.8551
NCI-H28 CTRP2; CTRP1 3.0584 17.0408 -2.6713 31.3912
NCI-H2052 CTRP2; CTRP1 3.9023 55.2892 -21.0265 43.3039
MPP 89 CTRP2 7.0606 22.1477 -1.8905 21.803
IST-Mes1 CTRP2 12.6586 33.553 -3.4731 17.8846
JL-1 CTRP2 15.9354 39.0586 -3.9709 15.5724
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC CTRP2 -14.3243 11.1796 -18.0376 72.9169
DU145 CTRP2 -12.2234 34.3064 -25.6469 61.2143
VCaP CTRP2 -8.873 24.4454 -17.776 60.2181
22Rv1 CTRP2 -6.3512 30.1653 -17.933 55.73
NCI-H660 CTRP2 0.4868 16.3999 -4.7681 40.7465
PaCa-3 CTRP2; CTRP1 10.2541 91.3344 -33.8295 41.5034
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 CTRP2 7.9193 53.395 -16.7788 37.8433
YD-15 CTRP2 11.5521 25.3658 -0.3411 11.3855
Cancer Drug Sensitivity Data Curated from 33 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ECC10 CTRP2 -15.6706 -0.3659 -16.3484 85.3636
HGC-27 CTRP2 -13.246 17.7641 -19.4063 67.8622
SNU-16 CTRP2 -10.5185 11.267 -13.969 68.5184
Fu97 CTRP2; CTRP1 -10.4896 25.6082 -19.9281 61.7974
NCC-StC-K140 CTRP2 -9.6556 27.81 -20.095 60.2374
GSS CTRP2 -7.912 0.3542 -8.1449 75.6515
SNU-620 CTRP2 -3.3284 15.879 -8.3071 52.3378
NCI-N87 CTRP2 -3.3079 13.7883 -7.3615 52.527
MKN74 CTRP2; CTRP1 -3.0596 77.2128 -37.9886 50.4133
NUGC-4 CTRP2; CTRP1 -2.8326 31.087 -15.0013 50.6021
SNU-1 CTRP2 -1.7644 55.5201 -26.0703 49.3369
SNU-216 CTRP2 -1.0622 50.7339 -23.0696 48.5297
SNU-5 CTRP2 -0.6578 45.2701 -19.9979 47.8678
HuG1-N CTRP2 -0.3356 173.472 -83.6937 49.3289
IM95 CTRP2 -0.1761 35.1936 -14.5749 46.5203
23132/87 CTRP2 1.3317 30.7799 -11.0348 44.0228
AGS CTRP1 3.848 7.4044 2.77 25.62
SNU-601 CTRP2 4.3262 26.0242 -6.0499 34.1403
Hs 746.T CTRP2 4.4155 4.9873 4.3728 4.338
SNU-668 CTRP2 4.6276 31.352 -8.4583 36.2292
KE-39 CTRP2 5.0733 37.4009 -11.1098 37.7196
KATO III CTRP2 5.0867 28.7581 -6.7772 33.7487
GSU CTRP2 5.849 6.5607 4.8067 0.1728
ECC12 CTRP2 6.7655 7.8274 4.7026 0.0902
MKN1 CTRP2 8.7352 44.5922 -11.7441 33.7458
SNU-719 CTRP2 9.3167 31.3696 -4.7496 24.4823
NUGC-3 CTRP2 9.4423 30.9476 -4.4499 23.7695
MKN7 CTRP2; CTRP1 12.8864 44.8025 -8.7275 26.2123
SH-10-TC CTRP2; CTRP1 15.5381 63.8537 -16.1284 30.7735
LMSU CTRP2 17.5535 46.0154 -6.1915 18.0989
SNU-1077 CTRP2 5.2155 44.5429 -14.5624 39.585
SNG-M CTRP2; CTRP1 10.6934 51.217 -13.5091 33.1033
SNU-685 CTRP2 14.668 32.2543 -1.6238 11.6085
⏷ Show the Full List of 33 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 10 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ML-1 [Human leukemia] CTRP2 -0.2952 39.7374 -16.9308 47.0732
CAL-62 CTRP2 4.9836 5.9103 4.5597 2.1577
BHT-101 CTRP2 7.2072 12.431 2.9604 5.3474
8505C CTRP2 9.2347 57.4018 -17.7294 37.0873
FTC-133 CTRP2 9.788 64.9957 -21.0756 38.1316
SW579 CTRP2 9.8328 62.5215 -19.8076 37.552
8305C CTRP2 10.0901 20.2652 1.1147 8.5421
TT CTRP2 10.3302 29.4164 -3.0671 19.8038
TT2609-C02 CTRP2 12.2935 31.864 -2.912 17.0814
FTC-238 CTRP2 12.3713 24.289 0.6242 7.74
⏷ Show the Full List of 10 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SCC-4 CTRP2 -15.407 3.0048 -16.7527 81.2
HSC-2 CTRP2; CTRP1 -11.6863 -10.0945 -11.6863 99.5711
HSC-4 CTRP2 -11.4323 -9.4372 -11.4323 98.9027
HSC-3 CTRP2 -7.2347 -6.6733 -7.2347 81.8048
BICR 22 CTRP2 -4.1919 66.1151 -33.4929 51.3461
SNU-1214 CTRP2 -1.2685 40.1285 -18.0014 48.4392
SNU-46 CTRP2 -0.8441 283.1897 -138.9653 49.6875
PE/CA-PJ34 (clone C12) CTRP2 -0.0062 87.1555 -40.2924 48.4582
FaDu CTRP2 1.511 81.5882 -36.2104 47.2877
YD-10B CTRP2 3.3626 22.5689 -5.156 34.7679
CAL-33 CTRP2 4.2519 12.9413 0.4176 20.3203
SCC-25 CTRP2 4.5178 29.35 -7.55 35.5178
CAL-27 CTRP2 5.7972 56.9601 -20.2888 41.2987
BICR 18 CTRP2 6.2367 41.7679 -12.3334 37.0843
SNU-1041 CTRP2 6.603 23.6613 -2.9991 25.1341
Detroit 562 CTRP2 7.3053 27.0379 -4.1296 26.2517
PE/CA-PJ15 CTRP2 8.3056 52.1506 -15.8492 36.9723
BICR 31 CTRP2 8.4104 25.056 -2.3136 20.7303
SNU-899 CTRP2 8.7176 29.2102 -4.1306 24.1672
BICR 16 CTRP2 9.1727 51.8877 -15.032 35.6338
SNU-1066 CTRP2 9.9536 30.6841 -3.9501 22.1351
BICR 56 CTRP2 10.4922 42.8183 -9.5169 29.6739
BHY CTRP2 11.4579 31.1126 -3.1098 18.4941
SNU-1076 CTRP2 12.3416 25.5355 0.0517 9.4295
YD-8 CTRP2 12.4861 35.9474 -4.7314 20.5568
PE/CA-PJ41 (clone D2) CTRP2 13.1919 42.87 -7.5839 24.3676
SCC-9 CTRP2; CTRP1 13.2246 47.3127 -9.7099 27.0379
PE/CA-PJ49 CTRP2 13.3999 41.8181 -6.9308 23.2108
BICR 6 CTRP2 13.5427 38.1739 -5.0855 20.0483
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
J82 CTRP2 -15.9449 0.8323 -16.8645 84.0092
UM-UC-1 CTRP2 -11.7456 -9.6823 -11.7456 99.1242
SCaBER CTRP2 -11.4118 -8.3712 -11.4118 97.2216
HT-1197 CTRP2 -11.4001 -9.2821 -11.4001 98.6924
253J CTRP2 -10.0078 -5.2805 -10.0117 90.2171
UM-UC-3 CTRP2; CTRP1 -9.3699 1.1852 -9.8243 77.3415
KU-19-19 CTRP2 -6.4368 -5.9925 -6.4368 76.4891
SW1710 CTRP2 -4.9864 20.4771 -12.0633 55.2471
JMSU-1 CTRP2 -4.4935 31.3005 -16.6858 53.8208
RT-4 CTRP2; CTRP1 -2.0252 4.491 -2.5248 47.5702
5637 CTRP2; CTRP1 -1.4731 82.508 -39.2353 49.3609
BC-3C CTRP2 0.5452 51.7014 -22.132 46.8043
HT-1376 CTRP2; CTRP1 0.5641 25.2651 -8.9974 43.5631
KMBC-2 CTRP2; CTRP1 0.705 285.9197 -139.016 49.3919
RT-112 CTRP2 2.7412 32.6274 -10.7106 40.7785
U-BLC1 CTRP2 2.9157 41.6093 -15.0409 42.5363
BFTC-905 CTRP2 4.5427 5.0913 4.4833 3.552
CAL-29 CTRP2 4.674 5.3579 4.5261 3.0182
253J-BV CTRP2 5.0325 8.0705 3.5214 6.4242
639V CTRP2 6.7577 7.8174 4.7032 0.0908
VM-CUB-1 CTRP2 10.3893 29.6998 -3.1631 19.9374
T24 CTRP2 10.4806 62.8981 -19.4863 36.862
TCCSUP CTRP2 10.6479 50.1195 -13.0106 32.746
647V CTRP2 13.5381 42.1172 -6.9798 23.14
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 8.9131 33.4798 -6.092 27.2226

References

1 The metagenome of Caracolus marginella gut microbiome using culture independent approaches and shotgun sequencing. Data Brief. 2017 Nov 22;16:501-505.
2 Structural analysis of the Streptomyces avermitilis CYP107W1-oligomycin A complex and role of the tryptophan 178 residue. Mol Cells. 2016 Mar;39(3):211-6.