Details of the Drug

General Information of Drug (ID: DM60RWZ)

Drug Name

2-(2-chlorophenyl)-2,2-diphenylethanamide

Synonyms

CHEMBL406683; AC1NNFGO; Amino-2-chlorotrityl resin; SCHEMBL1001586; 2-Chlorotriphenylmethyl amine resin; (2-chlorophenyl)-diphenylmethanamine; 2-Chlorotrityl amine, polymer-bound; BDBM50371377; 2-Chlorotrityl amine, polymer-bound, 100-200 mesh, extent of labeling: 1.3-1.8 mmol/g loading, 1 % cross-linked

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

#Ro5 Violations (Lipinski): 0

Molecular Weight (mw)

293.8

Logarithm of the Partition Coefficient (xlogp)

4.7

Rotatable Bond Count (rotbonds)

3

Hydrogen Bond Donor Count (hbonddonor)

1

Hydrogen Bond Acceptor Count (hbondacc)

1

Chemical Identifiers

Formula: C19H16ClN
IUPAC Name: (2-chlorophenyl)-diphenylmethanamine
Canonical SMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3Cl)N
InChI: InChI=1S/C19H16ClN/c20-18-14-8-7-13-17(18)19(21,15-9-3-1-4-10-15)16-11-5-2-6-12-16/h1-14H,21H2
InChIKey: AXCRTHNDHLRNOA-UHFFFAOYSA-N

Cross-matching ID

PubChem CID: 5068018
CAS Number: 42074-69-1
TTD ID: D0I5YS

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Calcium-activated potassium channel (KCN)	TTMNI76	NOUNIPROTAC	Inhibitor	[1]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	Novel inhibitors of the Gardos channel for the treatment of sickle cell disease. J Med Chem. 2008 Feb 28;51(4):976-82.