Details of the Drug

General Information of Drug (ID: DM6DULC)

• Drug Name: CAR-T Cells targeting Mesothelin

Indication

Disease Entry	ICD 11	Status	REF
Pancreatic cancer	2C10	Phase 1	[1]

• Drug Type: CAR T Cell Therapy
• Cross-matching ID: TTD ID: D0L7OJ

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Mesothelin (MSLN)	TT4RXME	MSLN_HUMAN	CAR-T-Cell-Therapy	[1]

Molecular Expression Atlas of This Drug

• ICD Disease Classification: 02 Neoplasm
• Disease Class: ICD-11: 2C82 Prostate cancer
• The Studied Tissue: Pancreas
• The Studied Disease: Pancreatic cancer [ICD-11:2C82]

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Mesothelin (MSLN)	DTT	MSLN	2.86E-20	3.98	6.12

References

• [1] ClinicalTrials.gov (NCT03267173) Evaluate the Safety and Efficacy of CAR-T in the Treatment of Pancreatic Cancer.